Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.200 None 1.000 32 9 1989 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.200 None 1.000 21 67 1992 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.090 None 1.000 9 0 2001 2019
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
MT-CO2 pseudogene 12 703 0.368 0.962 0.080 None 1.000 8 0 2001 2019
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.080 None 1.000 8 0 2001 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.170 None 1.000 8 2 2005 2018
Entrez Id: 182
Gene Symbol: JAG1
JAG1
P78504 jagged canonical Notch ligand 1 420 0.429 0.808 1.00 0.070 None 0.857 7 0 2013 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.150 None 1.000 6 5 1997 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.060 None 1.000 6 0 2006 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.060 None 1.000 6 0 2013 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.150 None 1.000 6 27 2005 2020
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.050 None 1.000 5 0 1998 2016
Entrez Id: 174
Gene Symbol: AFP
AFP
P02771 alpha fetoprotein Transporter 392 0.429 0.885 1.1E-11 0.050 None 1.000 5 0 2003 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.440 None 1.000 5 8 2014 2018
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 731 0.380 0.808 1.00 0.140 None 1.000 5 4 2014 2017
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.040 None 0.750 4 0 2009 2019
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.040 None 1.000 4 0 2010 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.040 None 0.750 4 0 2004 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.040 None 1.000 4 0 2005 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.040 None 1.000 4 0 2004 2018
Entrez Id: 10276
Gene Symbol: NET1
NET1
Q7Z628 neuroepithelial cell transforming 1 44 0.663 0.538 2.1E-06 0.040 None 1.000 4 0 2006 2014
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.040 None 1.000 4 0 1996 2020
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.130 None 1.000 4 4 2005 2019
Entrez Id: 9314
Gene Symbol: KLF4
KLF4
O43474 Kruppel like factor 4 Nucleic acid binding 307 0.449 0.769 1.00 0.030 None 1.000 3 0 2007 2014
Entrez Id: 100124700
Gene Symbol: HOTAIR
HOTAIR
HOX transcript antisense RNA 234 0.475 0.769 0.030 None 1.000 3 0 2014 2017