Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
O75874 isocitrate dehydrogenase (NADP(+)) 1 399 0.424 0.808 2.6E-12 0.400 None 0.971 35 2 2013 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.600 None 1.000 28 6 1995 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.600 None 0.957 23 1 1994 2019
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 731 0.380 0.808 1.00 0.400 None 1.000 18 0 2014 2019
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
P48735 isocitrate dehydrogenase (NADP(+)) 2 380 0.434 0.808 0.88 0.400 None 1.000 16 0 2013 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.100 None 1.000 13 0 2015 2020
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.400 None 1.000 11 0 2013 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.400 None 1.000 11 0 2007 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.380 None 1.000 9 0 2002 2019
Entrez Id: 174
Gene Symbol: AFP
AFP
P02771 alpha fetoprotein Transporter 392 0.429 0.885 1.1E-11 0.080 None 1.000 8 0 2010 2020
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.370 None 1.000 8 0 2006 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.080 None 1.000 8 0 2017 2020
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.080 None 0.875 8 0 2012 2019
Entrez Id: 3880
Gene Symbol: KRT19
KRT19
P08727 keratin 19 270 0.460 0.731 4.3E-03 0.080 None 1.000 8 0 2017 2019
Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC
P98088 mucin 5AC, oligomeric mucus/gel-forming Enzyme modulator 224 0.483 0.808 1.0E-08 0.070 None 0.857 7 0 2003 2019
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
Q86U86 polybromo 1 Epigenetic regulator 105 0.566 0.615 1.00 0.370 None 1.000 7 0 2013 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.070 None 1.000 7 2 2013 2019
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
O14497 AT-rich interaction domain 1A 341 0.455 0.846 1.00 0.370 None 1.000 7 0 2013 2019
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.060 None 1.000 6 0 2016 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.060 None 1.000 6 0 2015 2018
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.050 None 1.000 5 0 2008 2018
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.050 None 1.000 5 0 2001 2007
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.050 None 0.800 5 0 2010 2019
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.050 None 0.800 5 0 1999 2019
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
P15941 mucin 1, cell surface associated 594 0.384 0.885 1.9E-02 0.050 None 1.000 5 0 2001 2019