Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 1.000 limited 0.981 17 1 1975 2019
Entrez Id: 7421
Gene Symbol: VDR
VDR 		P11473 vitamin D receptor Nuclear receptor 757 0.352 0.885 1.7E-05 0.050 None 0.800 5 3 2014 2020
Entrez Id: 1298
Gene Symbol: COL9A2
COL9A2 		Q14055 collagen type IX alpha 2 chain 70 0.572 0.769 1.0E-08 0.030 None 0.667 3 3 2011 2018
Entrez Id: 9507
Gene Symbol: ADAMTS4
ADAMTS4 		O75173 ADAM metallopeptidase with thrombospondin type 1 motif 4 Enzyme 79 0.582 0.692 2.0E-06 0.020 None 1.000 2 2 2016 2017
Entrez Id: 8200
Gene Symbol: GDF5
GDF5 		P43026 growth differentiation factor 5 Signaling 70 0.511 0.692 0.67 0.020 None 1.000 2 1 2011 2018
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		P50591 TNF superfamily member 10 Signaling 412 0.413 0.885 0.13 0.020 None 1.000 2 0 2015 2015
Entrez Id: 176
Gene Symbol: ACAN
ACAN 		P16112 aggrecan Extracellular structure 122 0.528 0.846 1.00 0.020 None 1.000 2 0 2017 2017
Entrez Id: 4314
Gene Symbol: MMP3
MMP3 		P08254 matrix metallopeptidase 3 Enzyme 400 0.408 0.885 5.7E-15 0.020 None 1.000 2 1 2014 2018
Entrez Id: 54829
Gene Symbol: ASPN
ASPN 		Q9BXN1 asporin 43 0.636 0.500 1.0E-07 0.010 None 1.000 1 0 2008 2008
Entrez Id: 693174
Gene Symbol: MIR589
MIR589 		microRNA 589 34 0.656 0.538 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1 		P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 555 0.380 0.885 0.50 0.010 None 1.000 1 0 2005 2005
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.010 None 1.000 1 0 2015 2015
Entrez Id: 11096
Gene Symbol: ADAMTS5
ADAMTS5 		Q9UNA0 ADAM metallopeptidase with thrombospondin type 1 motif 5 Enzyme 77 0.597 0.654 8.0E-07 0.010 None 1.000 1 2 2017 2017
Entrez Id: 8483
Gene Symbol: CILP
CILP 		O75339 cartilage intermediate layer protein 17 0.736 0.423 5.4E-26 0.010 None 1.000 1 1 2018 2018
Entrez Id: 8493
Gene Symbol: PPM1D
PPM1D 		O15297 protein phosphatase, Mg2+/Mn2+ dependent 1D Enzyme 135 0.513 0.808 2.2E-11 0.010 None 1.000 1 0 2017 2017
Entrez Id: 85480
Gene Symbol: TSLP
TSLP 		Q969D9 thymic stromal lymphopoietin 208 0.486 0.808 4.0E-03 0.010 None 1.000 1 0 2017 2017
Entrez Id: 8797
Gene Symbol: TNFRSF10A
TNFRSF10A 		O00220 TNF receptor superfamily member 10a 126 0.521 0.731 5.1E-15 0.010 None 1.000 1 2 2012 2012
Entrez Id: 8807
Gene Symbol: IL18RAP
IL18RAP 		O95256 interleukin 18 receptor accessory protein Receptor 34 0.674 0.577 2.2E-03 0.010 None 1.000 1 1 2019 2019
Entrez Id: 9469
Gene Symbol: CHST3
CHST3 		Q7LGC8 carbohydrate sulfotransferase 3 91 0.517 0.846 7.2E-03 0.010 None 1.000 1 0 2013 2013
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 323 0.431 0.846 6.9E-07 0.010 None 1.000 1 0 2013 2013
Entrez Id: 4513
Gene Symbol: COX2
COX2 		P00403 cytochrome c oxidase subunit II Enzyme 762 0.352 0.962 0.010 None 1.000 1 0 2005 2005
Entrez Id: 4322
Gene Symbol: MMP13
MMP13 		P45452 matrix metallopeptidase 13 Enzyme 256 0.452 0.923 7.9E-18 0.010 None 1.000 1 0 2015 2015
Entrez Id: 1299
Gene Symbol: COL9A3
COL9A3 		Q14050 collagen type IX alpha 3 chain 83 0.569 0.769 3.3E-12 0.010 None < 0.001 1 1 2018 2018
Entrez Id: 1301
Gene Symbol: COL11A1
COL11A1 		P12107 collagen type XI alpha 1 chain 104 0.495 0.846 1.00 0.010 None 1.000 1 2 2018 2018
Entrez Id: 196872
Gene Symbol: LINC00638
LINC00638 		long intergenic non-protein coding RNA 638 2 0.931 0.154 0.010 None 1.000 1 0 2019 2019