Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.030 None 1.000 3 0 1998 2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.030 None 1.000 3 0 2002 2018
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1
P02458 collagen type II alpha 1 chain 496 0.444 0.846 1.00 0.030 None 1.000 3 0 1990 2010
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.030 None 1.000 3 0 2000 2018
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 Transcription factor 470 0.415 0.923 0.80 0.020 None 1.000 2 0 2014 2016
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.020 None 1.000 2 0 2002 2003
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.020 None 1.000 2 0 2012 2014
Entrez Id: 3077
Gene Symbol: HFE
HFE
Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.020 None 1.000 2 2 2006 2006
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
P03956 matrix metallopeptidase 1 Enzyme 589 0.385 0.885 7.7E-18 0.020 None 0.500 2 0 2009 2019
Entrez Id: 637
Gene Symbol: BID
BID
P55957 BH3 interacting domain death agonist 117 0.555 0.808 1.6E-11 0.010 None < 0.001 1 0 2012 2012
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
P01009 serpin family A member 1 Enzyme modulator 482 0.410 0.923 6.8E-08 0.010 None 1.000 1 0 1990 1990
Entrez Id: 5245
Gene Symbol: PHB
PHB
P35232 prohibitin 177 0.511 0.846 0.76 0.010 None 1.000 1 0 2013 2013
Entrez Id: 5167
Gene Symbol: ENPP1
ENPP1
P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 247 0.498 0.808 5.0E-08 0.010 None 1.000 1 0 2005 2005
Entrez Id: 7965
Gene Symbol: AIMP2
AIMP2
Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 555 0.393 0.923 8.0E-03 0.010 None 1.000 1 0 2009 2009
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 81793
Gene Symbol: TLR10
TLR10
Q9BXR5 toll like receptor 10 71 0.592 0.654 3.5E-09 0.010 None 1.000 1 1 2018 2018
Entrez Id: 8200
Gene Symbol: GDF5
GDF5
P43026 growth differentiation factor 5 Signaling 238 0.511 0.692 0.67 0.010 None 1.000 1 0 2014 2014
Entrez Id: 9261
Gene Symbol: MAPKAPK2
MAPKAPK2
P49137 MAPK activated protein kinase 2 Kinase 82 0.587 0.769 1.00 0.010 None 1.000 1 0 2009 2009
Entrez Id: 4322
Gene Symbol: MMP13
MMP13
P45452 matrix metallopeptidase 13 Enzyme 328 0.452 0.923 7.9E-18 0.010 None 1.000 1 0 2009 2009
Entrez Id: 9402
Gene Symbol: GRAP2
GRAP2
O75791 GRB2 related adaptor protein 2 538 0.394 0.923 1.5E-04 0.010 None 1.000 1 0 2009 2009
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 Enzyme 473 0.408 0.885 5.7E-15 0.010 None 1.000 1 0 2009 2009
Entrez Id: 5307
Gene Symbol: PITX1
PITX1
P78337 paired like homeodomain 1 109 0.561 0.654 0.88 0.010 None 1.000 1 0 2013 2013
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.010 None 1.000 1 0 2009 2009
Entrez Id: 7130
Gene Symbol: TNFAIP6
TNFAIP6
P98066 TNF alpha induced protein 6 91 0.582 0.731 1.1E-06 0.010 None 1.000 1 0 2014 2014
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.010 None 1.000 1 0 2019 2019