Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.450 1.000 7 2 1991 2007
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.410 1.000 3 1 2007 2012
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.400 1.000 10 0 1990 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.400 8 3 2004 2012
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.400 4 1 1987 2016
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 686 0.355 0.897 1.00 0.340 0.750 4 0 2003 2015
Entrez Id: 841
Gene Symbol: CASP8
CASP8
Q14790 caspase 8 enzyme modulator; hydrolase; protease 283 0.443 0.793 2.8E-06 0.310 1.000 1 0 2013 2013
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1, DNA repair associated ligase 411 0.410 0.862 1.8E-28 0.310 1.000 1 0 2005 2005
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch 1 389 0.415 0.759 1.00 0.310 1.000 1 0 2014 2014
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase enzyme modulator 545 0.404 0.828 8.7E-02 0.310 1.000 1 0 1996 1996
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
Q15303 erb-b2 receptor tyrosine kinase 4 185 0.494 0.690 1.00 0.300 0 0
Entrez Id: 2033
Gene Symbol: EP300
EP300
Q09472 E1A binding protein p300 nucleic acid binding; transcription factor; transferase 322 0.489 0.828 1.00 0.300 0 0
Entrez Id: 57492
Gene Symbol: ARID1B
ARID1B
Q8NFD5 AT-rich interaction domain 1B 187 0.561 0.655 1.00 0.300 0 0
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
Q86U86 polybromo 1 73 0.590 0.517 1.00 0.300 0 0
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
Q04721 notch 2 287 0.474 0.724 1.00 0.300 0 0
Entrez Id: 2248
Gene Symbol: FGF3
FGF3
P11487 fibroblast growth factor 3 signaling molecule 149 0.554 0.690 9.7E-05 0.300 0 0
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 195 0.494 0.621 1.2E-23 0.300 0 0
Entrez Id: 3169
Gene Symbol: FOXA1
FOXA1
P55317 forkhead box A1 nucleic acid binding; transcription factor 68 0.590 0.586 0.24 0.300 0 0
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
O15530 3-phosphoinositide dependent protein kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 41 0.639 0.310 0.97 0.300 0 0
Entrez Id: 9175
Gene Symbol: MAP3K13
MAP3K13
O43283 mitogen-activated protein kinase kinase kinase 13 13 0.743 0.172 0.78 0.300 0 0
Entrez Id: 8924
Gene Symbol: HERC2
HERC2
O95714 HECT and RLD domain containing E3 ubiquitin protein ligase 2 enzyme modulator; nucleic acid binding 134 0.600 0.552 1.00 0.300 0 0
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
P23771 GATA binding protein 3 nucleic acid binding; transcription factor 208 0.477 0.793 0.90 0.300 0 0
Entrez Id: 8821
Gene Symbol: INPP4B
INPP4B
O15327 inositol polyphosphate-4-phosphatase type II B 42 0.642 0.483 0.53 0.300 0 0
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
P11362 fibroblast growth factor receptor 1 623 0.388 0.759 1.00 0.300 0 0
Entrez Id: 2249
Gene Symbol: FGF4
FGF4
P08620 fibroblast growth factor 4 signaling molecule 54 0.616 0.483 0.14 0.300 0 0