Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.560 0.833 8 4 2002 2016
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase kinase; nucleic acid binding; transferase 486 0.401 0.862 6.0E-46 0.500 1 5 2007 2007
Entrez Id: 6416
Gene Symbol: MAP2K4
MAP2K4
P45985 mitogen-activated protein kinase kinase 4 69 0.582 0.586 1.00 0.500 1 1 2007 2007
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
P22607 fibroblast growth factor receptor 3 558 0.417 0.759 1.8E-05 0.500 0 0
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.400 0.941 17 0 1990 2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.400 0.900 10 0 1993 2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.380 0.875 8 0 1993 2015
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene 452 0.418 0.724 1.00 0.310 1.000 2 1 2007 2008
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 nucleic acid binding 356 0.424 0.759 5.1E-05 0.310 1.000 1 0 2006 2006
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
P54278 PMS1 homolog 2, mismatch repair system component nucleic acid binding 154 0.526 0.586 1.2E-27 0.310 1.000 1 0 2010 2010
Entrez Id: 581
Gene Symbol: BAX
BAX
Q07812 BCL2 associated X, apoptosis regulator signaling molecule 267 0.450 0.862 0.30 0.310 1.000 1 0 2002 2002
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
Q969H0 F-box and WD repeat domain containing 7 enzyme modulator 140 0.511 0.759 1.00 0.310 1.000 1 0 2018 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.310 1.000 1 0 2016 2016
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene nucleic acid binding 436 0.396 0.759 1.00 0.310 1.000 1 0 1999 1999
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC, WNT signaling pathway regulator 462 0.397 0.828 1.00 0.310 1.000 1 0 1995 1995
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 189 0.495 0.586 2.2E-05 0.310 1.000 1 0 2010 2010
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.310 1.000 1 0 2005 2005
Entrez Id: 203447
Gene Symbol: NRK
NRK
Q7Z2Y5 Nik related kinase 7 0.834 0.172 1.00 0.300 1 1 2007 2007
Entrez Id: 57787
Gene Symbol: MARK4
MARK4
Q96L34 microtubule affinity regulating kinase 4 kinase; transferase 15 0.773 0.241 1.00 0.300 1 1 2007 2007
Entrez Id: 3815
Gene Symbol: KIT
KIT
P10721 KIT proto-oncogene receptor tyrosine kinase 462 0.394 0.759 0.99 0.300 1 2 2007 2007
Entrez Id: 83931
Gene Symbol: STK40
STK40
Q8N2I9 serine/threonine kinase 40 kinase; transferase 3 0.886 0.172 0.99 0.300 1 2 2007 2007
Entrez Id: 6196
Gene Symbol: RPS6KA2
RPS6KA2
Q15349 ribosomal protein S6 kinase A2 29 0.685 0.276 1.2E-02 0.300 1 1 2007 2007
Entrez Id: 79858
Gene Symbol: NEK11
NEK11
Q8NG66 NIMA related kinase 11 kinase; transferase 6 0.815 0.138 6.4E-21 0.300 1 3 2007 2007
Entrez Id: 29904
Gene Symbol: EEF2K
EEF2K
O00418 eukaryotic elongation factor 2 kinase 16 0.727 0.207 8.5E-20 0.300 1 1 2007 2007
Entrez Id: 5590
Gene Symbol: PRKCZ
PRKCZ
Q05513 protein kinase C zeta calcium-binding protein; kinase; transfer/carrier protein; transferase 64 0.619 0.483 0.58 0.300 1 1 2007 2007