Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.010 None 1.000 1 0 1993 1993
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 1.000 18 2 1994 2018
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.050 None 1.000 5 0 1995 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.040 None 1.000 4 0 1995 2014
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.010 None 1.000 1 0 1995 1995
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.100 None 1.000 28 1 1996 2020
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.100 None 0.929 14 1 1996 2019
Entrez Id: 4221
Gene Symbol: MEN1
MEN1
O00255 menin 1 364 0.444 0.808 1.00 0.080 None 1.000 8 0 1997 2014
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor Enzyme 372 0.443 0.846 8.0E-02 0.030 None 1.000 3 0 1997 2013
Entrez Id: 4296
Gene Symbol: MAP3K11
MAP3K11
Q16584 mitogen-activated protein kinase kinase kinase 11 Kinase 74 0.597 0.615 1.1E-02 0.010 None 1.000 1 0 1997 1997
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
Q96GD0 pyridoxal phosphatase Enzyme 149 0.533 0.731 0.26 0.010 None 1.000 1 0 1999 1999
Entrez Id: 641
Gene Symbol: BLM
BLM
P54132 BLM RecQ like helicase 158 0.535 0.808 1.5E-15 0.020 None 1.000 2 0 2001 2005
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.060 None 0.667 6 0 2002 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.160 None 0.833 6 1 2002 2016
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
P22897 mannose receptor C-type 1 431 0.413 0.846 0.94 0.050 None 1.000 5 0 2002 2017
Entrez Id: 11132
Gene Symbol: CAPN10
CAPN10
Q9HC96 calpain 10 Enzyme 58 0.621 0.577 6.9E-13 0.010 None 1.000 1 0 2003 2003
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.020 None 1.000 2 0 2004 2010
Entrez Id: 115761
Gene Symbol: ARL11
ARL11
Q969Q4 ADP ribosylation factor like GTPase 11 35 0.670 0.423 5.3E-03 0.050 None 1.000 5 3 2005 2006
Entrez Id: 6389
Gene Symbol: SDHA
SDHA
P31040 succinate dehydrogenase complex flavoprotein subunit A Enzyme 246 0.517 0.731 2.6E-10 0.010 None < 0.001 1 0 2005 2005
Entrez Id: 1113
Gene Symbol: CHGA
CHGA
P10645 chromogranin A 218 0.490 0.808 3.0E-02 0.010 None < 0.001 1 0 2005 2005
Entrez Id: 11073
Gene Symbol: TOPBP1
TOPBP1
Q92547 DNA topoisomerase II binding protein 1 48 0.644 0.692 1.00 0.010 None 1.000 1 1 2006 2006
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.040 None 1.000 4 2 2007 2017
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
P36897 transforming growth factor beta receptor 1 Kinase 347 0.451 0.885 0.85 0.010 None 1.000 1 0 2007 2007
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
P15941 mucin 1, cell surface associated 594 0.384 0.885 1.9E-02 0.010 None 1.000 1 0 2007 2007
Entrez Id: 4683
Gene Symbol: NBN
NBN
O60934 nibrin Nucleic acid binding 291 0.467 0.808 2.2E-16 0.030 None 1.000 3 0 2008 2016