Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.050 None 1.000 5 0 2015 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.020 None 1.000 2 0 2000 2000
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.010 None 1.000 1 0 2002 2002
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 285 0.477 0.885 1.00 0.010 None 1.000 1 0 2002 2002
Entrez Id: 5296
Gene Symbol: PIK3R2
PIK3R2
O00459 phosphoinositide-3-kinase regulatory subunit 2 Enzyme modulator 120 0.551 0.808 1.6E-02 0.010 None 1.000 1 0 2002 2002
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.010 None 1.000 1 0 2002 2002
Entrez Id: 54093
Gene Symbol: SETD4
SETD4
Q9NVD3 SET domain containing 4 15 0.780 0.346 4.0E-13 0.010 None 1.000 1 0 2020 2020
Entrez Id: 54776
Gene Symbol: PPP1R12C
PPP1R12C
Q9BZL4 protein phosphatase 1 regulatory subunit 12C 53 0.626 0.654 8.7E-02 0.010 None 1.000 1 0 2002 2002
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 470 0.418 0.885 0.85 0.010 None 1.000 1 0 2000 2000
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.010 None 1.000 1 0 1999 1999
Entrez Id: 9241
Gene Symbol: NOG
NOG
Q13253 noggin 206 0.518 0.731 0.89 0.010 None 1.000 1 0 2014 2014
Entrez Id: 6146
Gene Symbol: RPL22
RPL22
P35268 ribosomal protein L22 Nucleic acid binding 39 0.666 0.346 0.16 0.010 None 1.000 1 0 2012 2012
Entrez Id: 9139
Gene Symbol: CBFA2T2
CBFA2T2
O43439 CBFA2/RUNX1 partner transcriptional co-repressor 2 Transcription factor 64 0.615 0.654 1.00 0.010 None 1.000 1 0 2002 2002
Entrez Id: 8874
Gene Symbol: ARHGEF7
ARHGEF7
Q14155 Rho guanine nucleotide exchange factor 7 215 0.486 0.846 1.00 0.010 None 1.000 1 0 2002 2002
Entrez Id: 84444
Gene Symbol: DOT1L
DOT1L
Q8TEK3 DOT1 like histone lysine methyltransferase Epigenetic regulator 79 0.599 0.692 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 7295
Gene Symbol: TXN
TXN
P10599 thioredoxin 338 0.447 0.885 0.20 0.010 None 1.000 1 0 2006 2006
Entrez Id: 613
Gene Symbol: BCR
BCR
P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 392 0.431 0.885 0.99 0.010 None 1.000 1 0 2018 2018
Entrez Id: 6533
Gene Symbol: SLC6A6
SLC6A6
P31641 solute carrier family 6 member 6 Transporter 34 0.682 0.538 0.99 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6502
Gene Symbol: SKP2
SKP2
Q13309 S-phase kinase associated protein 2 204 0.492 0.808 0.96 0.010 None 1.000 1 0 2015 2015
Entrez Id: 648
Gene Symbol: BMI1
BMI1
P35226 BMI1 proto-oncogene, polycomb ring finger 309 0.448 0.808 0.94 0.010 None 1.000 1 0 2014 2014
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.010 None 1.000 1 0 2002 2002
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.010 None 1.000 1 0 2002 2002
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.010 None 1.000 1 0 2017 2017