Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4353
Gene Symbol: MPO
MPO
P05164 myeloperoxidase Enzyme 653 0.377 0.923 7.1E-15 0.100 None 0.965 57 0 2000 2020
Entrez Id: 5657
Gene Symbol: PRTN3
PRTN3
P24158 proteinase 3 Enzyme 215 0.503 0.808 3.8E-05 0.100 None 0.938 32 0 1996 2019
Entrez Id: 728
Gene Symbol: C5AR1
C5AR1
P21730 complement C5a receptor 1 G-protein coupled receptor 179 0.513 0.808 0.40 0.040 None 0.750 4 0 2014 2018
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
P16410 cytotoxic T-lymphocyte associated protein 4 722 0.369 0.923 0.94 0.040 None 1.000 4 0 2008 2013
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
P01009 serpin family A member 1 Enzyme modulator 482 0.410 0.923 6.8E-08 0.040 None 1.000 4 0 2002 2014
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
Q9NR96 toll like receptor 9 457 0.411 0.885 9.8E-06 0.030 None 1.000 3 0 2014 2020
Entrez Id: 474168
Gene Symbol: WG
WG
Wegener granulomatosis 61 0.595 0.808 0.030 None 1.000 3 0 2006 2019
Entrez Id: 727
Gene Symbol: C5
C5
P01031 complement C5 Enzyme modulator 129 0.550 0.731 8.1E-24 0.030 None 1.000 3 0 2015 2018
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.030 None 1.000 3 0 2013 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.030 None 1.000 3 0 2009 2017
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.020 None 1.000 2 0 2003 2013
Entrez Id: 2993
Gene Symbol: GYPA
GYPA
P02724 glycophorin A (MNS blood group) 136 0.538 0.885 1.1E-03 0.020 None 1.000 2 0 2014 2019
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.020 None 1.000 2 0 2017 2020
Entrez Id: 9332
Gene Symbol: CD163
CD163
Q86VB7 CD163 molecule Enzyme 369 0.427 0.846 8.3E-04 0.020 None 1.000 2 0 2018 2020
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 400 0.438 0.846 3.5E-21 0.020 None 1.000 2 1 2009 2012
Entrez Id: 7172
Gene Symbol: TPMT
TPMT
P51580 thiopurine S-methyltransferase 83 0.593 0.692 7.1E-06 0.020 None 1.000 2 0 2018 2019
Entrez Id: 49
Gene Symbol: ACR
ACR
P10323 acrosin Enzyme 230 0.493 0.846 1.2E-02 0.020 None 1.000 2 0 2017 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.020 None 1.000 2 0 2018 2020
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
Q8IUH3 RNA binding motif protein 45 557 0.383 0.846 2.1E-10 0.020 None 1.000 2 0 2015 2019
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
P81172 hepcidin antimicrobial peptide 377 0.433 0.846 8.2E-03 0.010 None 1.000 1 0 2018 2018
Entrez Id: 931
Gene Symbol: MS4A1
MS4A1
P11836 membrane spanning 4-domains A1 Receptor 451 0.411 0.846 5.1E-05 0.010 None 1.000 1 0 2018 2018
Entrez Id: 57126
Gene Symbol: CD177
CD177
Q8N6Q3 CD177 molecule 75 0.595 0.654 0.010 None 1.000 1 0 2014 2014
Entrez Id: 60498
Gene Symbol: IGAN1
IGAN1
IgA nephropathy 140 0.524 0.808 0.010 None 1.000 1 0 2018 2018
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
P35900 keratin 20 559 0.388 0.846 9.1E-11 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.010 None 1.000 1 0 2018 2018