Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		P21802 fibroblast growth factor receptor 2 Kinase 345 0.380 0.808 1.00 0.160 None 1.000 6 1 2008 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 972 0.324 0.962 1.00 0.100 None 0.984 548 1 1988 2020
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1 		P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 448 0.410 0.885 1.7E-05 0.100 None 0.989 89 1 2003 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 942 0.328 0.923 6.0E-03 0.100 None 1.000 35 0 1995 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.100 None 1.000 28 0 2009 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1077 0.322 0.885 1.00 0.100 None 1.000 21 0 2009 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1105 0.319 0.885 1.00 0.100 None 1.000 21 0 2009 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1087 0.320 0.885 1.4E-06 0.100 None 1.000 21 0 2009 2019
Entrez Id: 1019
Gene Symbol: CDK4
CDK4 		P11802 cyclin dependent kinase 4 Kinase 386 0.412 0.808 6.3E-02 0.100 None 1.000 20 0 2016 2020
Entrez Id: 5241
Gene Symbol: PGR
PGR 		P06401 progesterone receptor Nuclear receptor 341 0.426 0.885 5.1E-02 0.100 None 0.900 20 0 2005 2020
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 762 0.351 0.846 0.99 0.100 None 1.000 14 0 2006 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.100 None 1.000 13 3 2004 2018
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 748 0.344 0.923 0.89 0.100 None 1.000 13 0 1996 2019
Entrez Id: 3169
Gene Symbol: FOXA1
FOXA1 		P55317 forkhead box A1 Transcription factor 132 0.522 0.731 0.22 0.100 None 1.000 12 0 2006 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1011 0.311 0.962 0.98 0.090 None 1.000 9 1 2009 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		P05019 insulin like growth factor 1 1050 0.318 0.885 0.27 0.080 None 1.000 8 0 2007 2020
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6 		P10635 cytochrome P450 family 2 subfamily D member 6 345 0.437 0.885 1.1E-25 0.080 None 1.000 8 0 2010 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1294 0.291 0.885 0.56 0.070 None 1.000 7 0 2007 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 576 0.367 0.923 9.2E-29 0.070 None 0.857 7 0 2010 2018
Entrez Id: 8202
Gene Symbol: NCOA3
NCOA3 		Q9Y6Q9 nuclear receptor coactivator 3 Kinase 115 0.522 0.654 0.54 0.070 None 0.857 7 0 2001 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.070 None 1.000 7 0 2008 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 459 0.379 0.846 2.4E-25 0.060 None 0.833 6 0 2000 2019
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 765 0.343 0.885 1.00 0.060 None 1.000 6 0 2011 2019
Entrez Id: 116833
Gene Symbol: ANIB1
ANIB1 		aneurysm, intracranial berry 1 61 0.608 0.500 0.050 None 0.800 5 0 2001 2017
Entrez Id: 2852
Gene Symbol: GPER1
GPER1 		Q99527 G protein-coupled estrogen receptor 1 G-protein coupled receptor 172 0.505 0.731 0.57 0.050 None 1.000 5 0 2010 2017