Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.390 None 1.000 10 0 2006 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.560 None 1.000 8 0 2000 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.360 None 1.000 7 0 2007 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.340 None 1.000 6 0 1994 2015
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.050 None 1.000 5 0 2017 2019
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.330 None 1.000 4 0 2012 2019
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
O75874 isocitrate dehydrogenase (NADP(+)) 1 399 0.424 0.808 2.6E-12 0.330 None 1.000 4 0 2013 2019
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.310 None 1.000 3 0 2013 2015
Entrez Id: 51741
Gene Symbol: WWOX
WWOX
Q9NZC7 WW domain containing oxidoreductase Enzyme 356 0.453 0.808 1.2E-15 0.020 None 1.000 2 0 2009 2014
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.020 None 1.000 2 0 2015 2019
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
P48735 isocitrate dehydrogenase (NADP(+)) 2 380 0.434 0.808 0.88 0.310 None 1.000 2 0 2012 2013
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 731 0.380 0.808 1.00 0.310 None 1.000 2 0 2015 2017
Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1
Q15116 programmed cell death 1 497 0.402 0.846 0.42 0.020 None 0.500 2 0 2017 2017
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1
Q9NS23 Ras association domain family member 1 Enzyme modulator 400 0.420 0.808 4.9E-06 0.020 None 1.000 2 0 2005 2005
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.310 None 1.000 2 0 2008 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.310 None 1.000 2 0 2015 2016
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.020 None 1.000 2 0 2018 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.010 None 1.000 1 0 2008 2008
Entrez Id: 5567
Gene Symbol: PRKACB
PRKACB
P22694 protein kinase cAMP-activated catalytic subunit beta Kinase 33 0.670 0.577 0.35 0.300 None 1.000 1 0 2015 2015
Entrez Id: 55810
Gene Symbol: FOXJ2
FOXJ2
Q9P0K8 forkhead box J2 15 0.821 0.154 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.010 None < 0.001 1 0 2014 2014
Entrez Id: 57120
Gene Symbol: GOPC
GOPC
Q9HD26 golgi associated PDZ and coiled-coil motif containing 103 0.561 0.654 8.4E-04 0.010 None 1.000 1 0 2014 2014
Entrez Id: 51014
Gene Symbol: TMED7
TMED7
Q86XR7 Q9Y3B3 transmembrane p24 trafficking protein 7 Transporter 336 0.436 0.808 0.48 0.010 None 1.000 1 0 2014 2014
Entrez Id: 5715
Gene Symbol: PSMD9
PSMD9
O00233 proteasome 26S subunit, non-ATPase 9 Enzyme modulator 344 0.435 0.846 4.9E-06 0.010 None 1.000 1 0 2014 2014
Entrez Id: 5566
Gene Symbol: PRKACA
PRKACA
P17612 protein kinase cAMP-activated catalytic subunit alpha Kinase 88 0.606 0.692 0.97 0.300 None 1.000 1 0 2015 2015