Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker disease CTD_human Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats. 23792339 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker disease CTD_mouse Exacerbation of diabetes-induced testicular apoptosis by zinc deficiency is most likely associated with oxidative stress, p38 MAPK activation, and p53 activation in mice. 21078376 2011
Entrez Id: 4240
Gene Symbol: MFGE8
MFGE8 		0.300 Biomarker disease CTD_human Induction of lactadherin mediates the apoptosis of endothelial cells in response to advanced glycation end products and protective effects of grape seed procyanidin B2 and resveratrol. 21505870 2011
Entrez Id: 6376
Gene Symbol: CX3CL1
CX3CL1 		0.300 Biomarker disease CTD_human Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism. 20388520 2010
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress. 19478208 2009
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.300 Therapeutic disease CTD_human Antioxidant activity of costunolide and eremanthin isolated from Costus speciosus (Koen ex. Retz) Sm. 20709041 2010
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.300 Therapeutic disease CTD_human MnSOD and catalase transgenes demonstrate that protection of islets from oxidative stress does not alter cytokine toxicity. 15855331 2005
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism. 20388520 2010
Entrez Id: 5166
Gene Symbol: PDK4
PDK4 		0.300 Biomarker disease CTD_human Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone. 14563825 2004
Entrez Id: 3953
Gene Symbol: LEPR
LEPR 		0.300 Biomarker disease CTD_human Type 2 Diabetes Dysregulates Glucose Metabolism in Cardiac Progenitor Cells. 27151219 2016
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.300 Biomarker disease CTD_human MnSOD and catalase transgenes demonstrate that protection of islets from oxidative stress does not alter cytokine toxicity. 15855331 2005
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.300 Biomarker disease CTD_human Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis. 18829990 2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.300 Therapeutic disease CTD_human Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance. 18375438 2008
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.300 Biomarker disease CTD_human Protective effect of Gui Qi mixture on the progression of diabetic nephropathy in rats. 17177138 2006
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1 		0.300 Biomarker disease CTD_human Altered matrix metalloproteinases and tissue inhibitors of metalloproteinases in embryos from diabetic rats during early organogenesis. 21963884 2011
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		0.300 Biomarker disease CTD_human Radical scavenging effect of gliclazide in diabetic rats fed with a high cholesterol diet. 14871415 2004
Entrez Id: 857
Gene Symbol: CAV1
CAV1 		0.300 Biomarker disease CTD_human Resveratrol enhances GLUT-4 translocation to the caveolar lipid raft fractions through AMPK/Akt/eNOS signalling pathway in diabetic myocardium. 18266981 2008
Entrez Id: 2101
Gene Symbol: ESRRA
ESRRA 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.300 Biomarker disease CTD_human Radical scavenging effect of gliclazide in diabetic rats fed with a high cholesterol diet. 14871415 2004
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		0.300 Biomarker disease CTD_human Up-regulation of heme oxygenase provides vascular protection in an animal model of diabetes through its antioxidant and antiapoptotic effects. 16959961 2006
Entrez Id: 2309
Gene Symbol: FOXO3
FOXO3 		0.300 Biomarker disease CTD_human Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats. 23792339 2013
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.300 Biomarker disease CTD_human Investigation of ocular neovascularization-related genes and oxidative stress in diabetic rat eye tissues after resveratrol treatment. 22191573 2012
Entrez Id: 6550
Gene Symbol: SLC9A3
SLC9A3 		0.300 Biomarker disease CTD_human Effect of potent redox-modulating manganese porphyrin, MnTM-2-PyP, on the Na(+)/H(+) exchangers NHE-1 and NHE-3 in the diabetic rat. 20003708 2009
Entrez Id: 3667
Gene Symbol: IRS1
IRS1 		0.300 Biomarker disease CTD_human Taurine exerts hypoglycemic effect in alloxan-induced diabetic rats, improves insulin-mediated glucose transport signaling pathway in heart and ameliorates cardiac oxidative stress and apoptosis. 22138235 2012