×
Entrez Id:
100507436
Gene Symbol:
MICA
MICA
0.200
GeneticVariation
disease
BEFREE
MICA gene polymorphisms in an Italian paediatric series of juvenile Behçet disease .
12373294
2002
×
Entrez Id:
100507436
Gene Symbol:
MICA
MICA
0.200
Biomarker
disease
BEFREE
MICA is reported to be strongly associated with Behçet's disease (BD ), a multisysytemic inflammation disorder characterized by oral apthous ulcers, skin lesions and genital ulcers.
12753668
2003
×
Entrez Id:
4524
Gene Symbol:
MTHFR
MTHFR
0.090
GeneticVariation
disease
BEFREE
Methylenetetrahydrofolate reductase gene C677T mutation and plasma homocysteine level in Behçet's disease .
14504916
2003
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.100
GeneticVariation
disease
BEFREE
Endothelial nitric oxide synthase gene polymorphisms in Behçet's disease and rheumatic diseases with vasculitis.
14583572
2003
×
Entrez Id:
4210
Gene Symbol:
MEFV
MEFV
0.500
GeneticVariation
disease
BEFREE
MEFV mutations are increased in Behçet's disease (BD ) and are associated with vascular involvement.
14727457
2004
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.100
GeneticVariation
disease
BEFREE
eNOS gene polymorphisms are associated with BD , which might contribute to the reduced NO activity observed in BD patients.
15705632
2005
×
Entrez Id:
3593
Gene Symbol:
IL12B
IL12B
0.050
GeneticVariation
disease
BEFREE
Interleukin-12B heterozygosity is associated with Behçet's disease susceptibility and plays an important role in mediating T helper type 1 antistreptococcal immune response.
18281862
2008
TNFRSF13C
0.010
AlteredExpression
disease
BEFREE
BAFF-R expression on B cells was increased in BD patients with vasculitis.
19026118
2009
×
Entrez Id:
3812
Gene Symbol:
KIR3DL2
KIR3DL2
0.040
GeneticVariation
disease
BEFREE
Killer cell immunoglobulin-like receptor genotypes in Behçet's disease patients: any role for the 3DP1*001/002 pseudogene?
19405872
2009
×
Entrez Id:
3806
Gene Symbol:
KIR2DS1
KIR2DS1
0.030
GeneticVariation
disease
BEFREE
Killer cell immunoglobulin-like receptor genotypes in Behçet's disease patients: any role for the 3DP1*001/002 pseudogene?
19405872
2009
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.100
GeneticVariation
disease
BEFREE
eNOS gene polymorphisms associated with BD are not associated with RAS.
19410237
2009
×
Entrez Id:
4792
Gene Symbol:
NFKBIA
NFKBIA
0.020
GeneticVariation
disease
BEFREE
IkappaBalpha promoter polymorphisms in patients with Behçet's disease .
20164548
2010
×
Entrez Id:
51561
Gene Symbol:
IL23A
IL23A
0.080
Biomarker
disease
BEFREE
IL-23 has been shown to be involved in the pathogenesis of Behcet's disease (BD ) through promoting IL-17 production.
20375120
2010
×
Entrez Id:
3105
Gene Symbol:
HLA-A
HLA-A
0.100
Biomarker
disease
BEFREE
HLA-A *02:07, A*26:01, and A*30:04 were associated with increased risk for BD , while HLA-A *33:03 with decreased risk.
21429233
2011
×
Entrez Id:
4210
Gene Symbol:
MEFV
MEFV
0.500
Biomarker
disease
BEFREE
MEFV gene analysis was performed in all the patients with BD and healthy controls; twelve different regions were scanned.
21901355
2012
×
Entrez Id:
3447
Gene Symbol:
IFNA13
IFNA13
0.020
Biomarker
disease
BEFREE
IFN-α had been used clinically in treating BD with uveitis with beneficial efficacy ever since the 1980s.
22197901
2012
×
Entrez Id:
3439
Gene Symbol:
IFNA1
IFNA1
0.020
Biomarker
disease
BEFREE
IFN-α had been used clinically in treating BD with uveitis with beneficial efficacy ever since the 1980s.
22197901
2012
×
Entrez Id:
7128
Gene Symbol:
TNFAIP3
TNFAIP3
0.090
GeneticVariation
disease
BEFREE
TNFAIP3 gene polymorphisms confer risk for Behcet's disease in a Chinese Han population.
23161053
2013
×
Entrez Id:
3553
Gene Symbol:
IL1B
IL1B
0.100
Biomarker
disease
BEFREE
IL-1β and ROS production of peptidoglycan (PGN)/lipopolysaccharide (LPS)-induced MDMs from active BD patients was significantly increased compared with inactive BD patients, AAU patients, and healthy controls.
23211828
2013
×
Entrez Id:
79001
Gene Symbol:
VKORC1
VKORC1
0.010
GeneticVariation
disease
BEFREE
VKORC1 polymorphisms seem not to be related with the thrombotic state of systemic and ocular Behçet's disease .
23362849
2014
×
Entrez Id:
23411
Gene Symbol:
SIRT1
SIRT1
0.010
Biomarker
disease
BEFREE
SIRT1 activator treatment in vitro using mouse pLN cells, normal human and ocular Behçet's disease donor PBMC resulted in suppressed T cell proliferation and pro-inflammatory cytokine production.
23395551
2013
×
Entrez Id:
2069
Gene Symbol:
EREG
EREG
0.010
GeneticVariation
disease
BEFREE
EREG -AREG and NRG1, which are members of the epidermal growth factor (EGF) family, seem to modulate BD susceptibility through main effects and gene-gene interactions.
23625463
2013
×
Entrez Id:
114609
Gene Symbol:
TIRAP
TIRAP
0.020
GeneticVariation
disease
BEFREE
TIRAP S180L gene polymorphism, which was previously shown to be associated with BD in a Caucasian population, has been replicated in either Turkish or Italian population in our study.
24064014
2013
×
Entrez Id:
3586
Gene Symbol:
IL10
IL10
0.700
Biomarker
disease
BEFREE
IL10 may be the susceptibility gene for BD in Chinese Han population.
24269690
2014
×
Entrez Id:
3105
Gene Symbol:
HLA-A
HLA-A
0.100
Biomarker
disease
BEFREE
HLA-A *26 was claimed as an additional BD susceptibility marker in Japanese and Greek patients.
24887019
2014