Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
0.100 Biomarker disease BEFREE Our data suggested MEG3 was involved in stem cell-like state of LCCs and curbed migration and invasion through miR-650/SLC34A2 axis in NSCLC. 31585300 2019
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
0.100 AlteredExpression disease BEFREE All these experiments were designed to investigate whether lncRNA MEG3 participated in the pathogenesis of NSCLC through inhibiting the expression of BRCA1 and Bcl-2 and promoting Bax expression. 30280775 2018
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
0.100 AlteredExpression disease BEFREE PTX significantly inhibited the proliferation of NSCLC cells and increased the expressions of MEG3 and P53. 30173893 2018
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
0.100 Biomarker disease BEFREE Mouse NSCLC transplanted tumor was established to verify the functional role of MEG3 in DDP resistance in vivo. 29123412 2017
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
0.100 AlteredExpression disease BEFREE However, the association between MEG3 expression and prognosis in non-small cell lung cancer (NSCLC) has not been fully investigated. 28782577 2017
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
0.100 AlteredExpression disease BEFREE In this study, we identified the expressing difference of several tumor-related lncRNAs in breast cancer samples and found that, MEG3, which is downregulated in non-small cell lung cancer (NSCLC) tumor tissues, is also downregulated in breast cancer samples compared with adjacent tissues. 27166155 2016
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
0.100 Biomarker disease BEFREE We therefore performed a meta-analysis on six lncRNAs (PVT1, AFAP1-AS1, LINC01133, ANRIL, MEG3 and UCA1) to clarify their prognostic roles in NSCLC. 27833074 2016
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
0.100 AlteredExpression disease BEFREE The levels of Meg3 and Skp2 were inversely correlated in NSCLC specimens. 26482610 2016
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
0.100 Biomarker disease BEFREE In conclusion, these results suggested that Meg3 may have a crucial role in the development of cisplatin resistance in non-small cell lung cancer. 26059239 2015
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
0.100 AlteredExpression disease BEFREE NSCLC cells transfected with pCDNA-MEG3 were injection into nude mice to study the effect of MEG3 on tumorigenesis in vivo . 24098911 2013