Gene: TNNT2 ×
Source: CLINVAR ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Disease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates. 22675533 2012
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy. 11106718 2000
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Cardiac troponin T lysine 210 deletion in a family with dilated cardiomyopathy. 11862580 2002
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Clinical and functional characterization of TNNT2 mutations identified in patients with dilated cardiomyopathy. 20031601 2009
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype. 15923195 2005
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy. 18612386 2008
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype. 15923195 2005
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR [Association of TNNT2 gene mutations with idiopathic dilated cardiomyopathy in a Chengdu population]. 19253838 2008
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Novel Genetic Variants in BAG3 and TNNT2 in a Swedish Family with a History of Dilated Cardiomyopathy and Sudden Cardiac Death. 28669108 2017
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Familial dilated cardiomyopathy mutations uncouple troponin I phosphorylation from changes in myofibrillar Ca²⁺ sensitivity. 23539503 2013
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform. 15623536 2005
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. 22517884 2012
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Mutation screening in dilated cardiomyopathy: prominent role of the beta myosin heavy chain gene. 15769782 2005
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer. 27153395 2016
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR The landscape of genetic variation in dilated cardiomyopathy as surveyed by clinical DNA sequencing. 24503780 2014
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Sarcomere gene mutations in isolated left ventricular noncompaction cardiomyopathy do not predict clinical phenotype. 21551322 2011
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Multiple Species Comparison of Cardiac Troponin T and Dystrophin: Unravelling the DNA behind Dilated Cardiomyopathy. 29367539 2017
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Ca(2+)-desensitizing effect of a deletion mutation Delta K210 in cardiac troponin T that causes familial dilated cardiomyopathy. 11773635 2002
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Dilated cardiomyopathy caused by a novel TNNT2 mutation-added value of genetic testing in the correct identification of affected subjects. 19324435 2010
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR A novel arginine to tryptophan (R144W) mutation in troponin T (cTnT) gene in an indian multigenerational family with dilated cardiomyopathy (FDCM). 24992688 2014
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Disease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates. 22675533 2012
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Cardiomyopathy-causing deletion K210 in cardiac troponin T alters phosphorylation propensity of sarcomeric proteins. 20079745 2010
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitization. 14654368 2003
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Different functional properties of troponin T mutants that cause dilated cardiomyopathy. 12923187 2003
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments. 17932326 2007