Gene: TNNT2 ×
Source: CLINVAR ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy. 11106718 2000
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Novel cardiac troponin T mutation as a cause of familial dilated cardiomyopathy. 11684629 2001
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Ca(2+)-desensitizing effect of a deletion mutation Delta K210 in cardiac troponin T that causes familial dilated cardiomyopathy. 11773635 2002
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Cardiac troponin T lysine 210 deletion in a family with dilated cardiomyopathy. 11862580 2002
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Different functional properties of troponin T mutants that cause dilated cardiomyopathy. 12923187 2003
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitization. 14654368 2003
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Novel troponin T mutation in familial dilated cardiomyopathy with gender-dependant severity. 15464434 2005
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy. 15542288 2004
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy. 15542288 2004
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform. 15623536 2005
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Mutation screening in dilated cardiomyopathy: prominent role of the beta myosin heavy chain gene. 15769782 2005
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype. 15923195 2005
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype. 15923195 2005
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments. 17932326 2007
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments. 17932326 2007
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Mutations in sarcomere protein genes in left ventricular noncompaction. 18506004 2008
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Mutations in sarcomere protein genes in left ventricular noncompaction. 18506004 2008
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy. 18612386 2008
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR [Association of TNNT2 gene mutations with idiopathic dilated cardiomyopathy in a Chengdu population]. 19253838 2008
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Dilated cardiomyopathy caused by a novel TNNT2 mutation-added value of genetic testing in the correct identification of affected subjects. 19324435 2010
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Coding sequence mutations identified in MYH7, TNNT2, SCN5A, CSRP3, LBD3, and TCAP from 313 patients with familial or idiopathic dilated cardiomyopathy. 19412328 2008
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Clinical and functional characterization of TNNT2 mutations identified in patients with dilated cardiomyopathy. 20031601 2009
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 GeneticVariation group CLINVAR Clinical and functional characterization of TNNT2 mutations identified in patients with dilated cardiomyopathy. 20031601 2009
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Cardiomyopathy-causing deletion K210 in cardiac troponin T alters phosphorylation propensity of sarcomeric proteins. 20079745 2010
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2 		0.630 CausalMutation group CLINVAR Recurrent and founder mutations in the Netherlands: mutation p.K217del in troponin T2, causing dilated cardiomyopathy. 20978592 2010