Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker phenotype CTD_mouse Manganese superoxide dismutase is a p53-regulated gene that switches cancers between early and advanced stages. 22009531 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker phenotype CTD_human A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. 15550242 2004
Entrez Id: 23314
Gene Symbol: SATB2
SATB2 		0.300 Biomarker phenotype CTD_human SATB2 expression increased anchorage-independent growth and cell migration in human bronchial epithelial cells. 26780400 2016
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1 		0.300 Biomarker phenotype CTD_human Reduced reactive oxygen species-generating capacity contributes to the enhanced cell growth of arsenic-transformed epithelial cells. 20516118 2010
Entrez Id: 4609
Gene Symbol: MYC
MYC 		0.300 Biomarker phenotype CTD_human Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention. 29626521 2018
Entrez Id: 653361
Gene Symbol: NCF1
NCF1 		0.300 Biomarker phenotype CTD_human NADPH oxidase activation is required in reactive oxygen species generation and cell transformation induced by hexavalent chromium. 21742780 2011
Entrez Id: 406947
Gene Symbol: MIR155
MIR155 		0.300 Biomarker phenotype CTD_human MicroRNA-155 regulates arsenite-induced malignant transformation by targeting Nrf2-mediated oxidative damage in human bronchial epithelial cells. 28688901 2017
Entrez Id: 10919
Gene Symbol: EHMT2
EHMT2 		0.300 Biomarker phenotype CTD_human Upregulation of histone-lysine methyltransferases plays a causal role in hexavalent chromium-induced cancer stem cell-like property and cell transformation. 29391238 2018
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		0.300 Biomarker phenotype CTD_human Up-regulation of cyclin D1 by JNK1/c-Jun is involved in tumorigenesis of human embryo lung fibroblast cells induced by a low concentration of arsenite. 21726611 2011
Entrez Id: 8668
Gene Symbol: EIF3I
EIF3I 		0.300 Biomarker phenotype CTD_human Molecular cloning and functional analysis of a novel cadmium-responsive proto-oncogene. 11830523 2002
Entrez Id: 8999
Gene Symbol: CDKL2
CDKL2 		0.300 Biomarker phenotype CTD_human CDKL2 promotes epithelial-mesenchymal transition and breast cancer progression. 25333262 2014
Entrez Id: 3866
Gene Symbol: KRT15
KRT15 		0.300 Biomarker phenotype CTD_human Overabundance of putative cancer stem cells in human skin keratinocyte cells malignantly transformed by arsenic. 22011395 2012
Entrez Id: 1950
Gene Symbol: EGF
EGF 		0.300 Biomarker phenotype CTD_human Inhibition of cell transformation by resveratrol and its derivatives: differential effects and mechanisms involved. 12687016 2003
Entrez Id: 8848
Gene Symbol: TSC22D1
TSC22D1 		0.300 Biomarker phenotype CTD_human Acute molecular markers of rodent hepatic carcinogenesis identified by transcription profiling. 15089088 2004
Entrez Id: 406988
Gene Symbol: MIR205
MIR205 		0.300 Biomarker phenotype CTD_human Aberrant expression of miR-638 contributes to benzo(a)pyrene-induced human cell transformation. 22048643 2012
Entrez Id: 2335
Gene Symbol: FN1
FN1 		0.300 Biomarker phenotype CTD_human MCF-7 cells expressing nuclear associated lysyl oxidase-like 2 (LOXL2) exhibit an epithelial-to-mesenchymal transition (EMT) phenotype and are highly invasive in vitro. 24014025 2013
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		0.300 Biomarker phenotype CTD_human Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via ROS-dependent activation of miR-21-PDCD4 signaling. 27323401 2016
Entrez Id: 3880
Gene Symbol: KRT19
KRT19 		0.300 Biomarker phenotype CTD_human Overabundance of putative cancer stem cells in human skin keratinocyte cells malignantly transformed by arsenic. 22011395 2012
Entrez Id: 5292
Gene Symbol: PIM1
PIM1 		0.300 Biomarker phenotype CTD_human Conditional transgenic expression of PIM1 kinase in prostate induces inflammation-dependent neoplasia. 23565217 2013
Entrez Id: 79605
Gene Symbol: PGBD5
PGBD5 		0.300 Biomarker phenotype CTD_human PGBD5 promotes site-specific oncogenic mutations in human tumors. 28504702 2017
Entrez Id: 2353
Gene Symbol: FOS
FOS 		0.300 Biomarker phenotype CTD_human Suppression of oncogene-induced transformation by quercetin and retinoic acid in rat liver epithelial cells. 8777434 1995
Entrez Id: 406899
Gene Symbol: MIR106A
MIR106A 		0.300 Biomarker phenotype CTD_human miR-106a-mediated malignant transformation of cells induced by anti-benzo[a]pyrene-trans-7,8-diol-9,10-epoxide. 20889678 2011
Entrez Id: 100506658
Gene Symbol: OCLN
OCLN 		0.300 Biomarker phenotype CTD_human MCF-7 cells expressing nuclear associated lysyl oxidase-like 2 (LOXL2) exhibit an epithelial-to-mesenchymal transition (EMT) phenotype and are highly invasive in vitro. 24014025 2013
Entrez Id: 406961
Gene Symbol: MIR185
MIR185 		0.300 Biomarker phenotype CTD_human Aberrant expression of miR-638 contributes to benzo(a)pyrene-induced human cell transformation. 22048643 2012
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R 		0.300 Biomarker phenotype CTD_human Repression of miR-143 mediates Cr (VI)-induced tumor angiogenesis via IGF-IR/IRS1/ERK/IL-8 pathway. 23748240 2013