Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 GeneticVariation group CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968 2014
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 GeneticVariation group CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968 2014
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR Regorafenib in metastatic colorectal cancer. 24559322 2014
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR Prognostic role of PIK3CA mutation in colorectal cancer: cohort study and literature review. 22357840 2012
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR Phosphatidylinositide-3-kinase inhibitors: addressing questions of isoform selectivity and pharmacodynamic/predictive biomarkers in early clinical trials. 22162582 2012
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors. 22162589 2012
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. 20619739 2010
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR Predictive biomarkers of sensitivity to the phosphatidylinositol 3' kinase inhibitor GDC-0941 in breast cancer preclinical models. 20453058 2010
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 GeneticVariation group CLINVAR PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer. 19366826 2009
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR PIK3CA mutations predict local recurrences in rectal cancer patients. 19903786 2009
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer. 19366826 2009
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies. 19223544 2009
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling. 18725974 2008
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 GeneticVariation group CLINVAR Functional analysis of PIK3CA gene mutations in human colorectal cancer. 15930273 2005
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. 15647370 2005
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR The PIK3CA gene is mutated with high frequency in human breast cancers. 15254419 2004
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.490 CausalMutation group CLINVAR High frequency of mutations of the PIK3CA gene in human cancers. 15016963 2004