Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5319
Gene Symbol: PLA2G1B
PLA2G1B 		0.010 GeneticVariation group BEFREE Mutations in pantothenate kinase 2 (PANK2) and phospholipase A2 (PLA2G6) cause recessive, childhood-onset extrapyramidal disorders termed pantothenate kinase-associated neurodegeneration (PKAN) and infantile neuroaxonal dystrophy (INAD), respectively. 21496576 2011
Entrez Id: 8398
Gene Symbol: PLA2G6
PLA2G6 		0.010 GeneticVariation group BEFREE Mutations in pantothenate kinase 2 (PANK2) and phospholipase A2 (PLA2G6) cause recessive, childhood-onset extrapyramidal disorders termed pantothenate kinase-associated neurodegeneration (PKAN) and infantile neuroaxonal dystrophy (INAD), respectively. 21496576 2011
Entrez Id: 7534
Gene Symbol: YWHAZ
YWHAZ 		0.010 GeneticVariation group BEFREE Mutations in pantothenate kinase 2 (PANK2) and phospholipase A2 (PLA2G6) cause recessive, childhood-onset extrapyramidal disorders termed pantothenate kinase-associated neurodegeneration (PKAN) and infantile neuroaxonal dystrophy (INAD), respectively. 21496576 2011
Entrez Id: 10367
Gene Symbol: MICU1
MICU1 		0.300 Biomarker group CTD_human Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. 24336167 2014
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB 		0.300 Biomarker group CTD_human Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export. 25938945 2015
Entrez Id: 9213
Gene Symbol: XPR1
XPR1 		0.300 Biomarker group CTD_human Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export. 25938945 2015
Entrez Id: 5159
Gene Symbol: PDGFRB
PDGFRB 		0.300 Biomarker group CTD_human Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export. 25938945 2015
Entrez Id: 6575
Gene Symbol: SLC20A2
SLC20A2 		0.300 Biomarker group CTD_human Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export. 25938945 2015
Entrez Id: 5617
Gene Symbol: PRL
PRL 		0.320 Biomarker group BEFREE Our findings demonstrate that there is moderate to high level of evidence suggesting that in the treatment of schizophrenia, LAI SGAs have higher efficacy and are associated with higher rates of extrapyramidal syndrome and prolactin-related symptoms. 30466208 2018
Entrez Id: 5617
Gene Symbol: PRL
PRL 		0.320 GeneticVariation group BEFREE The most frequently reported were ADRs related to extrapyramidal syndrome (14.7%), breast disorders or blood prolactin level changes (4.7%), and cardiac arrhythmias (4.6%). 30676073 2019