Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.360 | Biomarker | disease | BEFREE | Fifty-one consecutive patients of AKI following vasculotoxic snake bite were evaluated for various clinical/biochemical parameters (including Free T4, TSH, Cortisol, ACTH, total testosterone, FSH, LH, prolactin, and IGF-1). | 31556012 | 2019 | ||||
|
0.360 | AlteredExpression | disease | BEFREE | Thus, our study indicated that enhancement of UC-MSCs bioactivities with IGF-1 overexpression could increase the UC-MSCs therapeutic potential and further developed a new therapeutic strategy for the treatment of AKI. | 26830766 | 2016 | ||||
|
0.360 | Biomarker | disease | BEFREE | Our preliminary findings suggest that IGF-I is locally produced in the kidney during the recovery period of ARF and might play roles in the repair processes, and extend the experimental observations in animal models into human pathophysiology. | 10499309 | 1999 | ||||
|
0.360 | Biomarker | disease | BEFREE | Exogenous administration of some growth factors, such as IGF-I, EGF and HGF, accelerates recovery of renal function in experimental acute renal failure (ARF). | 9541273 | 1998 | ||||
|
0.360 | AlteredExpression | disease | BEFREE | IGF-IR mRNA was decreased in renal cortex and medulla of both ARF groups and was not detected in liver in any group. | 9767523 | 1998 | ||||
|
0.360 | Biomarker | disease | BEFREE | Further studies to determine the role of IGF-I as a therapeutic agent for acute renal failure and its utility as a medical therapy for chronic renal insufficiency are required. | 9255221 | 1997 | ||||
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0.360 | Therapeutic | disease | CTD_human | Solution hybridization RNAase protection assays showed that renal IGF-1 mRNA, IGF-1 receptor (IGF-1R) mRNA, and IGF-binding protein-1 (IGFBP-1) mRNA were unaffected by exogenous IGF-1, but this treatment significantly increased renal IGF-1 in ARF rats compared with normal rats and ARF rats not receiving IGF-1. | 7540432 | 1995 |