Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4200
Gene Symbol: ME2
ME2 		0.310 GeneticVariation disease BEFREE The present study suggests that genetic variation in or near the ME2 gene is associated with both psychotic and manic disorders, including schizophrenia and bipolar disorder. 17258816 2007
Entrez Id: 6285
Gene Symbol: S100B
S100B 		0.500 Biomarker disease CTD_human Regionally specific changes in levels of cortical S100beta in bipolar 1 disorder but not schizophrenia. 16476148 2006
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A 		0.500 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 6285
Gene Symbol: S100B
S100B 		0.500 Biomarker disease RGD Increased cerebrospinal fluid levels of S100B protein in rat model of mania induced by ouabain. 15581912 2004
Entrez Id: 6285
Gene Symbol: S100B
S100B 		0.500 Biomarker disease CTD_human Increased cerebrospinal fluid levels of S100B protein in rat model of mania induced by ouabain. 15581912 2004
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A 		0.500 Biomarker disease RGD The genetic association database. 15118671 2004
Entrez Id: 4200
Gene Symbol: ME2
ME2 		0.310 Biomarker disease PSYGENET The present study suggests that genetic variation in or near the ME2 gene is associated with both psychotic and manic disorders, including schizophrenia and bipolar disorder. 17258816 2007
Entrez Id: 6863
Gene Symbol: TAC1
TAC1 		0.300 Biomarker disease CTD_human Down-regulation of amygdala preprotachykinin A mRNA but not 3H-SP receptor binding sites in subjects affected by mood disorders and schizophrenia. 15845098 2005
Entrez Id: 85458
Gene Symbol: DIXDC1
DIXDC1 		0.300 Biomarker disease CTD_human DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling. 27752079 2018
Entrez Id: 1109
Gene Symbol: AKR1C4
AKR1C4 		0.300 Biomarker disease CTD_human AKR1C4 gene variant associated with low euthymic serum progesterone and a history of mood irritability in males with bipolar disorder. 21570127 2011
Entrez Id: 26011
Gene Symbol: TENM4
TENM4 		0.300 Biomarker disease CTD_human Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. 21926972 2011
Entrez Id: 6671
Gene Symbol: SP4
SP4 		0.300 Biomarker disease CTD_human Transcription factor SP4 is a susceptibility gene for bipolar disorder. 19401786 2009
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.300 Biomarker disease CTD_human Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review. 17074966 2007
Entrez Id: 22999
Gene Symbol: RIMS1
RIMS1 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 2572
Gene Symbol: GAD2
GAD2 		0.300 Biomarker disease CTD_human GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and Reelin proteins in cerebellum. 15560956 2005
Entrez Id: 4729
Gene Symbol: NDUFV2
NDUFV2 		0.300 Biomarker disease CTD_human Expression of mitochondrial complex I subunit gene NDUFV2 in the lymphoblastoid cells derived from patients with bipolar disorder and schizophrenia. 19135101 2009
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B 		0.300 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010
Entrez Id: 10014
Gene Symbol: HDAC5
HDAC5 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 2898
Gene Symbol: GRIK2
GRIK2 		0.300 Biomarker disease CTD_human Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania. 18332879 2008
Entrez Id: 5649
Gene Symbol: RELN
RELN 		0.300 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 54877
Gene Symbol: ZCCHC2
ZCCHC2 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 288
Gene Symbol: ANK3
ANK3 		0.300 Biomarker disease CTD_human Genome-wide association study identifies five new schizophrenia loci. 21926974 2011
Entrez Id: 7222
Gene Symbol: TRPC3
TRPC3 		0.300 Biomarker disease CTD_human Chronic oxidative stress modulates TRPC3 and TRPM2 channel expression and function in rat primary cortical neurons: relevance to the pathophysiology of bipolar disorder. 23602965 2013
Entrez Id: 6196
Gene Symbol: RPS6KA2
RPS6KA2 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 5142
Gene Symbol: PDE4B
PDE4B 		0.300 Biomarker disease CTD_human PDE4B polymorphisms and decreased PDE4B expression are associated with schizophrenia. 18394866 2008