Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 815
Gene Symbol: CAMK2A
CAMK2A
0.200 Biomarker disease MGD
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK
0.200 Biomarker disease MGD
Entrez Id: 478
Gene Symbol: ATP1A3
ATP1A3
0.200 Biomarker disease MGD
Entrez Id: 5428
Gene Symbol: POLG
POLG
0.200 Biomarker disease MGD
Entrez Id: 1109
Gene Symbol: AKR1C4
AKR1C4
0.300 Biomarker disease CTD_human AKR1C4 gene variant associated with low euthymic serum progesterone and a history of mood irritability in males with bipolar disorder. 21570127 2011
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
0.300 Biomarker disease CTD_human Art, alpha-1-antitrypsin polymorphisms and intense creative energy: blessing or curse? 17659342 2007
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Biomarker disease CTD_human Association studies of the BDNF and the NTRK2 gene polymorphisms with prophylactic lithium response in bipolar patients. 19018715 2008
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
0.300 Biomarker disease CTD_human Association studies of the BDNF and the NTRK2 gene polymorphisms with prophylactic lithium response in bipolar patients. 19018715 2008
Entrez Id: 3630
Gene Symbol: INS
INS
0.300 Biomarker disease CTD_human Carbohydrate metabolism in mania before and after lithium carbonate treatment. 5506046 1970
Entrez Id: 1312
Gene Symbol: COMT
COMT
0.300 Biomarker disease CTD_human Catechol o-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder. 11772685 2002
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.300 Biomarker disease CTD_human Catechol o-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder. 11772685 2002
Entrez Id: 7222
Gene Symbol: TRPC3
TRPC3
0.300 Biomarker disease CTD_human Chronic oxidative stress modulates TRPC3 and TRPM2 channel expression and function in rat primary cortical neurons: relevance to the pathophysiology of bipolar disorder. 23602965 2013
Entrez Id: 7226
Gene Symbol: TRPM2
TRPM2
0.300 Biomarker disease CTD_human Chronic oxidative stress modulates TRPC3 and TRPM2 channel expression and function in rat primary cortical neurons: relevance to the pathophysiology of bipolar disorder. 23602965 2013
Entrez Id: 8553
Gene Symbol: BHLHE40
BHLHE40
0.300 Biomarker disease CTD_human Circadian polymorphisms in night owls, in bipolars, and in non-24-hour sleep cycles. 25395965 2014
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
0.300 Biomarker disease CTD_human Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. 18711365 2008
Entrez Id: 288
Gene Symbol: ANK3
ANK3
0.300 Biomarker disease CTD_human Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. 18711365 2008
Entrez Id: 84628
Gene Symbol: NTNG2
NTNG2
0.300 Biomarker disease CTD_human Decreased mRNA expression of netrin-G1 and netrin-G2 in the temporal lobe in schizophrenia and bipolar disorder. 17507910 2008
Entrez Id: 22854
Gene Symbol: NTNG1
NTNG1
0.300 Biomarker disease CTD_human Decreased mRNA expression of netrin-G1 and netrin-G2 in the temporal lobe in schizophrenia and bipolar disorder. 17507910 2008
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
0.300 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010
Entrez Id: 2931
Gene Symbol: GSK3A
GSK3A
0.300 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010
Entrez Id: 85458
Gene Symbol: DIXDC1
DIXDC1
0.300 Biomarker disease CTD_human DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling. 27752079 2018
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
0.300 Biomarker disease CTD_human Dopamine D1 receptor gene polymorphism is associated with prophylactic lithium response in bipolar disorder. 19153942 2009
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
0.300 Biomarker disease CTD_human Down-regulation of amygdala preprotachykinin A mRNA but not 3H-SP receptor binding sites in subjects affected by mood disorders and schizophrenia. 15845098 2005
Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D
0.300 Biomarker disease CTD_human Enhancing VTA Cav1.3 L-type Ca2+ channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens. 28194001 2017
Entrez Id: 2898
Gene Symbol: GRIK2
GRIK2
0.300 Biomarker disease CTD_human Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania. 18332879 2008