×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Clinical features associated with CTNNB1 de novo loss of function mutations in ten individuals.
27915094
2017
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Defects in the Cell Signaling Mediator β-Catenin Cause the Retinal Vascular Condition FEVR.
28575650
2017
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
De novo mutations in beta-catenin (CTNNB1) appear to be a frequent cause of intellectual disability: expanding the mutational and clinical spectrum.
25326669
2015
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Large-scale discovery of novel genetic causes of developmental disorders.
25533962
2015
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features.
24614104
2014
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
A new intellectual disability syndrome caused by CTNNB1 haploinsufficiency.
24668549
2014
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Chondrocyte β-catenin signaling regulates postnatal bone remodeling through modulation of osteoclast formation in a murine model.
24431282
2014
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Mutations in WNT1 cause different forms of bone fragility.
23499309
2013
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Diagnostic exome sequencing in persons with severe intellectual disability.
23033978
2012
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Wnt/β-catenin signaling and disease.
22682243
2012
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Specific armadillo repeat sequences facilitate β-catenin nuclear transport in live cells via direct binding to nucleoporins Nup62, Nup153, and RanBP2/Nup358.
22110128
2012
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations.
22495309
2012
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Maintaining embryonic stem cell pluripotency with Wnt signaling.
21903672
2011
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Crystal structure of a full-length beta-catenin.
18334222
2008
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis.
15866164
2005
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes.
15866163
2005
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Wnt/beta-catenin pathway.
15713948
2005
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development.
11719191
2001
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Establishment of the dorso-ventral axis in Xenopus embryos is presaged by early asymmetries in beta-catenin that are modulated by the Wnt signaling pathway.
9060476
1997
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Lack of beta-catenin affects mouse development at gastrulation.
8582267
1995
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
The product of the Drosophila segment polarity gene armadillo is part of a multi-protein complex resembling the vertebrate adherens junction.
8227220
1993
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
0.100
CausalMutation
group
CLINVAR
Purification of a 92-kDa cytoplasmic protein tightly associated with the cell-cell adhesion molecule E-cadherin (uvomorulin). Characterization and extractability of the protein complex from the cell cytostructure.
1999432
1991