Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10371
Gene Symbol: SEMA3A
SEMA3A
0.010 Biomarker phenotype LHGDN Increased class 3 semaphorin expression modulates the invasive and adhesive properties of prostate cancer cells. 17390026 2007
Entrez Id: 10512
Gene Symbol: SEMA3C
SEMA3C
0.010 Biomarker phenotype LHGDN Increased class 3 semaphorin expression modulates the invasive and adhesive properties of prostate cancer cells. 17390026 2007
Entrez Id: 100133941
Gene Symbol: CD24
CD24
0.010 Biomarker phenotype LHGDN Isolation of CD24(high) and CD24(low/-) cells from MCF-7: CD24 expression is positively related with proliferation, adhesion and invasion in MCF-7. 17950993 2007
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
0.010 AlteredExpression phenotype LHGDN Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas. 15637590 2005
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.010 AlteredExpression phenotype LHGDN The role of nitric oxide synthases and nitrotyrosine in retinoblastoma. 15754329 2005
Entrez Id: 9211
Gene Symbol: LGI1
LGI1
0.010 Biomarker phenotype LHGDN Suppression of the cell proliferation and invasion phenotypes in glioma cells by the LGI1 gene. 12821932 2003
Entrez Id: 146664
Gene Symbol: MGAT5B
MGAT5B
0.010 Biomarker phenotype LHGDN N-acetylglucosaminyltransferase V expression levels regulate cadherin-associated homotypic cell-cell adhesion and intracellular signaling pathways. 14561752 2003
Entrez Id: 2113
Gene Symbol: ETS1
ETS1
0.010 AlteredExpression phenotype LHGDN Stromal expression of invasion-promoting, matrix-degrading proteases MMP-1 and -9 and the Ets 1 transcription factor in HNPCC carcinomas and sporadic colorectal cancers. 12949792 2003
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
0.200 Biomarker phenotype RGD Expression of angiogenic factors is upregulated in DMBA-induced rat mammary pathologies. 15459484 2004
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
0.300 Biomarker phenotype CTD_human Long Noncoding RNA (lncRNA) MIR22HG Suppresses Gastric Cancer Progression through Attenuating NOTCH2 Signaling. 30670679 2019
Entrez Id: 100126335
Gene Symbol: MIR543
MIR543
0.300 Therapeutic phenotype CTD_human miR-543 inhibites cervical cancer growth and metastasis by targeting TRPM7. 30710498 2019
Entrez Id: 54822
Gene Symbol: TRPM7
TRPM7
0.300 Biomarker phenotype CTD_human miR-543 inhibites cervical cancer growth and metastasis by targeting TRPM7. 30710498 2019
Entrez Id: 693124
Gene Symbol: MIR532
MIR532
0.300 Biomarker phenotype CTD_human Downregulation of microRNA-532-5p promotes the proliferation and invasion of bladder cancer cells through promotion of HMGB3/Wnt/β-catenin signaling. 30639441 2019
Entrez Id: 406966
Gene Symbol: MIR191
MIR191
0.300 Biomarker phenotype CTD_human MicroRNA-191, regulated by HIF-2α, is involved in EMT and acquisition of a stem cell-like phenotype in arsenite-transformed human liver epithelial cells. 29277653 2018
Entrez Id: 100126343
Gene Symbol: MIR874
MIR874
0.300 Therapeutic phenotype CTD_human Upregulation of miR-874-3p and miR-874-5p inhibits epithelial ovarian cancer malignancy via SIK2. 30004169 2018
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
0.300 Biomarker phenotype CTD_human Involvement of HIF-1α-regulated miR-21, acting via the Akt/NF-κB pathway, in malignant transformation of HBE cells induced by cigarette smoke extract. 29501572 2018
Entrez Id: 92140
Gene Symbol: MTDH
MTDH
0.300 Biomarker phenotype CTD_human MicroRNA-1271 suppresses the proliferation and invasion of colorectal cancer cells by regulating metadherin/Wnt signaling. 29315995 2018
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.300 Biomarker phenotype CTD_human Involvement of HIF-1α-regulated miR-21, acting via the Akt/NF-κB pathway, in malignant transformation of HBE cells induced by cigarette smoke extract. 29501572 2018
Entrez Id: 5970
Gene Symbol: RELA
RELA
0.300 Biomarker phenotype CTD_human Involvement of HIF-1α-regulated miR-21, acting via the Akt/NF-κB pathway, in malignant transformation of HBE cells induced by cigarette smoke extract. 29501572 2018
Entrez Id: 100302203
Gene Symbol: MIR1271
MIR1271
0.300 Biomarker phenotype CTD_human MicroRNA-1271 suppresses the proliferation and invasion of colorectal cancer cells by regulating metadherin/Wnt signaling. 29315995 2018
Entrez Id: 4751
Gene Symbol: NEK2
NEK2
0.300 Biomarker phenotype CTD_human Deguelin inhibits epithelial-to-mesenchymal transition and metastasis of human non-small cell lung cancer cells by regulating NIMA-related kinase 2. 28509438 2017
Entrez Id: 3158
Gene Symbol: HMGCS2
HMGCS2
0.300 Biomarker phenotype CTD_human HMGCS2 enhances invasion and metastasis via direct interaction with PPARα to activate Src signaling in colorectal cancer and oral cancer. 27816970 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
0.300 Biomarker phenotype CTD_human Estrogen and ERα enhanced β-catenin degradation and suppressed its downstream target genes to block the metastatic function of HA22T hepatocellular carcinoma cells via modulating GSK-3β and β-TrCP expression. 26990689 2017
Entrez Id: 100126328
Gene Symbol: MIR940
MIR940
0.300 Therapeutic phenotype CTD_human Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs. 28423620 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
0.300 Therapeutic phenotype CTD_human Estrogen and ERα enhanced β-catenin degradation and suppressed its downstream target genes to block the metastatic function of HA22T hepatocellular carcinoma cells via modulating GSK-3β and β-TrCP expression. 26990689 2017