Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8091
Gene Symbol: HMGA2
HMGA2
0.300 Biomarker phenotype CTD_human HMGA2 upregulation mediates Cd-induced migration and invasion in A549 cells and in lung tissues of mice. 28830677 2017
Entrez Id: 196
Gene Symbol: AHR
AHR
0.300 Therapeutic phenotype CTD_human Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial-mesenchymal transition in non-small cell lung cancer cells. 27752740 2017
Entrez Id: 406947
Gene Symbol: MIR155
MIR155
0.300 Biomarker phenotype CTD_human MIR155 Regulation of Ubiquilin1 and Ubiquilin2: Implications in Cellular Protection and Tumorigenesis. 28315615 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.300 Biomarker phenotype CTD_human Estrogen and ERα enhanced β-catenin degradation and suppressed its downstream target genes to block the metastatic function of HA22T hepatocellular carcinoma cells via modulating GSK-3β and β-TrCP expression. 26990689 2017
Entrez Id: 406997
Gene Symbol: MIR215
MIR215
0.300 Therapeutic phenotype CTD_human The long noncoding RNA PCAT-1 links the microRNA miR-215 to oncogene CRKL-mediated signaling in hepatocellular carcinoma. 28887306 2017
Entrez Id: 283120
Gene Symbol: H19
H19
0.300 Biomarker phenotype CTD_human Long non-coding RNA H19 promotes the proliferation and invasion of breast cancer through upregulating DNMT1 expression by sponging miR-152. 28544374 2017
Entrez Id: 1488
Gene Symbol: CTBP2
CTBP2
0.300 Biomarker phenotype CTD_human Transforming activity and therapeutic targeting of C-terminal-binding protein 2 in Apc-mutated neoplasia. 28414304 2017
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
0.300 Biomarker phenotype CTD_human Long non-coding RNA H19 promotes the proliferation and invasion of breast cancer through upregulating DNMT1 expression by sponging miR-152. 28544374 2017
Entrez Id: 4627
Gene Symbol: MYH9
MYH9
0.300 Biomarker phenotype CTD_human Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma. 28650484 2017
Entrez Id: 4660
Gene Symbol: PPP1R12B
PPP1R12B
0.300 Biomarker phenotype CTD_human Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma. 28650484 2017
Entrez Id: 7159
Gene Symbol: TP53BP2
TP53BP2
0.300 Biomarker phenotype CTD_human Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma. 28650484 2017
Entrez Id: 406933
Gene Symbol: MIR141
MIR141
0.300 Therapeutic phenotype CTD_human Trans-nonachlor decreases miR-141-3p levels in human melanocytes in vitro promoting melanoma cell characteristics and shows a multigenerational impact on miR-8 levels in Drosophila. 27616325 2016
Entrez Id: 8518
Gene Symbol: ELP1
ELP1
0.300 Biomarker phenotype CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
Entrez Id: 91801
Gene Symbol: ALKBH8
ALKBH8
0.300 Biomarker phenotype CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
0.300 Therapeutic phenotype CTD_human Elevated IL-1β expression induces invasiveness of triple negative breast cancer cells and is suppressed by zerumbone. 27567548 2016
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
0.300 Biomarker phenotype CTD_human Transcription factor activity of estrogen receptor α activation upon nonylphenol or bisphenol A treatment enhances the in vitro proliferation, invasion, and migration of neuroblastoma cells. 27366082 2016
Entrez Id: 7913
Gene Symbol: DEK
DEK
0.300 Biomarker phenotype CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
Entrez Id: 442911
Gene Symbol: MIR346
MIR346
0.300 Biomarker phenotype CTD_human miR-346 promotes migration and invasion of nasopharyngeal carcinoma cells via targeting BRMS1. 27501413 2016
Entrez Id: 90353
Gene Symbol: CTU1
CTU1
0.300 Biomarker phenotype CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
Entrez Id: 79727
Gene Symbol: LIN28A
LIN28A
0.300 Biomarker phenotype CTD_human MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells. 26910839 2016
Entrez Id: 1950
Gene Symbol: EGF
EGF
0.300 Biomarker phenotype CTD_human Gallic acid-capped gold nanoparticles inhibit EGF-induced MMP-9 expression through suppression of p300 stabilization and NFκB/c-Jun activation in breast cancer MDA-MB-231 cells. 27634460 2016
Entrez Id: 348180
Gene Symbol: CTU2
CTU2
0.300 Biomarker phenotype CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
Entrez Id: 7431
Gene Symbol: VIM
VIM
0.300 Biomarker phenotype CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
0.300 Therapeutic phenotype CTD_human Transcription factor activity of estrogen receptor α activation upon nonylphenol or bisphenol A treatment enhances the in vitro proliferation, invasion, and migration of neuroblastoma cells. 27366082 2016
Entrez Id: 1000
Gene Symbol: CDH2
CDH2
0.300 Biomarker phenotype CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016