Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.300 Biomarker phenotype CTD_human Mangiferin exerts antitumor activity in breast cancer cells by regulating matrix metalloproteinases, epithelial to mesenchymal transition, and β-catenin signaling pathway. 23707762 2013
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		0.300 Therapeutic phenotype CTD_human Elevated IL-1β expression induces invasiveness of triple negative breast cancer cells and is suppressed by zerumbone. 27567548 2016
Entrez Id: 9891
Gene Symbol: NUAK1
NUAK1 		0.300 Biomarker phenotype CTD_human DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer. 26213588 2015
Entrez Id: 27250
Gene Symbol: PDCD4
PDCD4 		0.300 Biomarker phenotype CTD_human Resveratrol reduces prostate cancer growth and metastasis by inhibiting the Akt/MicroRNA-21 pathway. 23272133 2012
Entrez Id: 7704
Gene Symbol: ZBTB16
ZBTB16 		0.300 Biomarker phenotype CTD_human DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer. 26213588 2015
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7 		0.300 Biomarker phenotype CTD_human Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines. 18844224 2009
Entrez Id: 406966
Gene Symbol: MIR191
MIR191 		0.300 Biomarker phenotype CTD_human MicroRNA-191, regulated by HIF-2α, is involved in EMT and acquisition of a stem cell-like phenotype in arsenite-transformed human liver epithelial cells. 29277653 2018
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13 		0.300 Biomarker phenotype CTD_human DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer. 26213588 2015
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.300 Biomarker phenotype CTD_human Resveratrol suppresses epithelial-to-mesenchymal transition in colorectal cancer through TGF-β1/Smads signaling pathway mediated Snail/E-cadherin expression. 25884904 2015
Entrez Id: 1950
Gene Symbol: EGF
EGF 		0.300 Biomarker phenotype CTD_human Cdk4/6 inhibition induces epithelial-mesenchymal transition and enhances invasiveness in pancreatic cancer cells. 22869556 2012
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.300 Biomarker phenotype CTD_human N-Hydroxycinnamide derivatives of osthole inhibit cell migration and invasion by suppressing Smad2 and Akt pathways in human colorectal adenocarcinoma cells. 24727557 2014
Entrez Id: 4751
Gene Symbol: NEK2
NEK2 		0.300 Biomarker phenotype CTD_human Deguelin inhibits epithelial-to-mesenchymal transition and metastasis of human non-small cell lung cancer cells by regulating NIMA-related kinase 2. 28509438 2017
Entrez Id: 79026
Gene Symbol: AHNAK
AHNAK 		0.300 Biomarker phenotype CTD_human Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells. 20388789 2010
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.300 Biomarker phenotype CTD_human Transcription factor activity of estrogen receptor α activation upon nonylphenol or bisphenol A treatment enhances the in vitro proliferation, invasion, and migration of neuroblastoma cells. 27366082 2016
Entrez Id: 7913
Gene Symbol: DEK
DEK 		0.300 Biomarker phenotype CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
Entrez Id: 442911
Gene Symbol: MIR346
MIR346 		0.300 Biomarker phenotype CTD_human miR-346 promotes migration and invasion of nasopharyngeal carcinoma cells via targeting BRMS1. 27501413 2016
Entrez Id: 7050
Gene Symbol: TGIF1
TGIF1 		0.300 Biomarker phenotype CTD_human TG-interacting factor transcriptionally induced by AKT/FOXO3A is a negative regulator that antagonizes arsenic trioxide-induced cancer cell apoptosis. 25791921 2015
Entrez Id: 8434
Gene Symbol: RECK
RECK 		0.300 Therapeutic phenotype CTD_human RECK-mediated inhibition of glioma migration and invasion. 20127710 2010
Entrez Id: 29979
Gene Symbol: UBQLN1
UBQLN1 		0.300 Biomarker phenotype CTD_human Ubiquilin1 represses migration and epithelial-to-mesenchymal transition of human non-small cell lung cancer cells. 24747970 2015
Entrez Id: 6282
Gene Symbol: S100A11
S100A11 		0.300 Biomarker phenotype CTD_human Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells. 20388789 2010
Entrez Id: 100126343
Gene Symbol: MIR874
MIR874 		0.300 Therapeutic phenotype CTD_human Upregulation of miR-874-3p and miR-874-5p inhibits epithelial ovarian cancer malignancy via SIK2. 30004169 2018
Entrez Id: 6913
Gene Symbol: TBX15
TBX15 		0.300 Biomarker phenotype CTD_human DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer. 26213588 2015
Entrez Id: 3855
Gene Symbol: KRT7
KRT7 		0.300 Biomarker phenotype CTD_human Variation of keratin 7 expression and other phenotypic characteristics of independent isolates of cadmium transformed human urothelial cells (UROtsa). 19921857 2010
Entrez Id: 3158
Gene Symbol: HMGCS2
HMGCS2 		0.300 Biomarker phenotype CTD_human HMGCS2 enhances invasion and metastasis via direct interaction with PPARα to activate Src signaling in colorectal cancer and oral cancer. 27816970 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.300 Biomarker phenotype CTD_human Estrogen and ERα enhanced β-catenin degradation and suppressed its downstream target genes to block the metastatic function of HA22T hepatocellular carcinoma cells via modulating GSK-3β and β-TrCP expression. 26990689 2017