Gene: MSH6 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Actionable exomic incidental findings in 6503 participants: challenges of variant classification. 25637381 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. 25980754 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer. 25370038 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Clinical characterization and mutation spectrum in Caribbean Hispanic families with Lynch syndrome. 25782445 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease. 25525159 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Combined Microsatellite Instability, MLH1 Methylation Analysis, and Immunohistochemistry for Lynch Syndrome Screening in Endometrial Cancers From GOG210: An NRG Oncology and Gynecologic Oncology Group Study. 26552419 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Combined Microsatellite Instability, MLH1 Methylation Analysis, and Immunohistochemistry for Lynch Syndrome Screening in Endometrial Cancers From GOG210: An NRG Oncology and Gynecologic Oncology Group Study. 26552419 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Glioblastomas, astrocytomas and oligodendrogliomas linked to Lynch syndrome. 25648859 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. 25980754 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Classification of Amino Acid Substitutions in Mismatch Repair Proteins Using PON-MMR2. 26333163 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Impact of an immunohistochemistry-based universal screening protocol for Lynch syndrome in endometrial cancer on genetic counseling and testing. 25617771 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic. 26023681 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Comprehensive screening for mutations associated with colorectal cancer in unselected cases reveals penetrant and nonpenetrant mutations. 25142776 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR The gastrointestinal manifestation of constitutional mismatch repair deficiency syndrome: from a single adenoma to polyposis-like phenotype and early onset cancer. 25307252 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Constitutional mismatch repair deficiency syndrome: clinical description in a French cohort. 26318770 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Genetic features of Lynch syndrome in the Israeli population. 25430799 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Mismatch repair genes founder mutations and cancer susceptibility in Lynch syndrome. 25345868 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Impact of an immunohistochemistry-based universal screening protocol for Lynch syndrome in endometrial cancer on genetic counseling and testing. 25617771 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Clinical and Molecular Characterization of Brazilian Patients Suspected to Have Lynch Syndrome. 26437257 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Somatic POLE mutations cause an ultramutated giant cell high-grade glioma subtype with better prognosis. 25740784 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Tumor mismatch repair immunohistochemistry and DNA MLH1 methylation testing of patients with endometrial cancer diagnosed at age younger than 60 years optimizes triage for population-level germline mismatch repair gene mutation testing. 24323032 2014
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Tumor mismatch repair immunohistochemistry and DNA MLH1 methylation testing of patients with endometrial cancer diagnosed at age younger than 60 years optimizes triage for population-level germline mismatch repair gene mutation testing. 24323032 2014
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Complex MSH2 and MSH6 mutations in hypermutated microsatellite unstable advanced prostate cancer. 25255306 2014
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR A massive parallel sequencing workflow for diagnostic genetic testing of mismatch repair genes. 24689082 2014
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population. 24728189 2014