Gene: MSH6 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Clinical Challenges Associated with Universal Screening for Lynch Syndrome-Associated Endometrial Cancer. 27965287 2017
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Teenage colorectal polyposis and cancer may be caused by constitutional mismatch repair deficiency (CMMRD). 27723366 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR A cohort analysis of men with a family history of BRCA1/2 and Lynch mutations for prostate cancer. 27456091 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Inherited Mutations in Women With Ovarian Carcinoma. 26720728 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Massively Parallel Sequencing-Based Clonality Analysis of Synchronous Endometrioid Endometrial and Ovarian Carcinomas. 26832770 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Mismatch repair deficiency concordance between primary colorectal cancer and corresponding metastasis. 26666765 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Lynch syndrome mutation spectrum in New South Wales, Australia, including 55 novel mutations. 27064304 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Co-occurrence of nonsense mutations in MSH6 and MSH2 in Lynch syndrome families evidencing that not all truncating mutations are equal. 26446363 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Mismatch repair gene mutation spectrum in the Swedish Lynch syndrome population. 27601186 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Germline multi-gene hereditary cancer panel testing in an unselected endometrial cancer cohort. 27443514 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Screening for germline mutations in breast/ovarian cancer susceptibility genes in high-risk families in Israel. 26687385 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer. 27153395 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers. 26648449 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Analysis of Lynch Syndrome Mismatch Repair Genes in Women with Endometrial Cancer. 27398995 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Mismatch repair gene mutation spectrum in the Swedish Lynch syndrome population. 27601186 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Incidental germline variants in 1000 advanced cancers on a prospective somatic genomic profiling protocol. 26787237 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Frequent mismatch-repair defects link prostate cancer to Lynch syndrome. 27013479 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Prevalence of Pathogenic Mutations in Cancer Predisposition Genes among Pancreatic Cancer Patients. 26483394 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR The gastrointestinal manifestation of constitutional mismatch repair deficiency syndrome: from a single adenoma to polyposis-like phenotype and early onset cancer. 25307252 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing. 25559809 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Characterization of a novel founder MSH6 mutation causing Lynch syndrome in the French Canadian population. 25318681 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Identification of germline genetic mutations in patients with pancreatic cancer. 26440929 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Germ-line variants identified by next generation sequencing in a panel of estrogen and cancer associated genes correlate with poor clinical outcome in Lynch syndrome patients. 26517685 2015