Gene: STK11 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group BEFREE Peutz-Jeghers Syndrome (PJS) is a hereditary cancer predisposing syndrome caused by autosomal dominant mutations in the serine/threonine kinase 11 (STK11) gene and is associated with decreased life expectancy. 29720104 2018
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Clinical characteristics and STK11 gene mutations in Chinese children with Peutz-Jeghers syndrome. 26607058 2015
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Genetic and Clinical Analyses of Southern Chinese Children with Peutz-Jeghers Syndrome. 26225618 2015
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Novel and recurrent mutations of STK11 gene in six Chinese cases with Peutz-Jeghers syndrome. 24604241 2014
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR STK11 domain XI mutations: candidate genetic drivers leading to the development of dysplastic polyps in Peutz-Jeghers syndrome. 24652667 2014
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR High Resolution Melting analysis as a rapid and efficient method of screening for small mutations in the STK11 gene in patients with Peutz-Jeghers syndrome. 23718779 2013
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Cancer risk associated with STK11/LKB1 germline mutations in Peutz-Jeghers syndrome patients: results of an Italian multicenter study. 23415580 2013
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps. 23399955 2013
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Insights into the phosphoryl transfer catalyzed by cAMP-dependent protein kinase: an X-ray crystallographic study of complexes with various metals and peptide substrate SP20. 23672593 2013
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Predicting the functional effect of amino acid substitutions and indels. 23056405 2012
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR An unusual case of sex cord tumor with annular tubules with malignant transformation in a patient with Peutz-Jeghers syndrome. 19952941 2010
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients. 21118512 2010
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients. 21118512 2010
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation. 19892943 2009
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation. 19892943 2009
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Novel mutations in the STK11 gene in Thai patients with Peutz-Jeghers syndrome. 19908348 2009
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation. 18687677 2008
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome. 17404884 2007
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Genetic defects underlying Peutz-Jeghers syndrome (PJS) and exclusion of the polarity-associated MARK/Par1 gene family as potential PJS candidates. 17924967 2007
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Cancer risks in LKB1 germline mutation carriers. 16407375 2006
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Frequency and spectrum of cancers in the Peutz-Jeghers syndrome. 16707622 2006
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR An updated mutation spectrum in an Australian series of PJS patients provides further evidence for only one gene locus. 17026623 2006
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Frequency and spectrum of cancers in the Peutz-Jeghers syndrome. 16707622 2006
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Exonic STK11 deletions are not a rare cause of Peutz-Jeghers syndrome. 16582077 2006
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR An updated mutation spectrum in an Australian series of PJS patients provides further evidence for only one gene locus. 17026623 2006