Gene: SDHB ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 GeneticVariation group BEFREE The hereditary cancer syndromes hereditary leiomyomatosis and renal cell cancer (HLRCC) and succinate dehydrogenase-related hereditary paraganglioma and pheochromocytoma (SDH PGL/PCC) are linked to germline loss-of-function mutations in genes encoding the Krebs cycle enzymes fumarate hydratase and succinate dehydrogenase, thus leading to elevated levels of fumarate and succinate, respectively<sup>1-3</sup>. 30013182 2018
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR Tumour risks and genotype-phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD. 29386252 2018
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR The penetrance of paraganglioma and pheochromocytoma in SDHB germline mutation carriers. 28503760 2018
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 GeneticVariation group CLINVAR The penetrance of paraganglioma and pheochromocytoma in SDHB germline mutation carriers. 28503760 2018
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR The phenotype of SDHB germline mutation carriers: a nationwide study. 28490599 2017
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR Leukoencephalopathy due to Complex II Deficiency and Bi-Allelic SDHB Mutations: Further Cases and Implications for Genetic Counselling. 27604842 2017
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR Calculating the optimal surveillance for head and neck paraganglioma in SDHB-mutation carriers. 27573198 2017
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR SDHB-related pheochromocytoma and paraganglioma penetrance and genotype-phenotype correlations. 28374168 2017
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 GeneticVariation group CLINVAR The phenotype of SDHB germline mutation carriers: a nationwide study. 28490599 2017
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR A Duodenal SDH-Deficient Gastrointestinal Stromal Tumor in a Patient With a Germline SDHB Mutation. 28324028 2017
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 GeneticVariation group CLINVAR SDHB-related pheochromocytoma and paraganglioma penetrance and genotype-phenotype correlations. 28374168 2017
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR A SDHC Founder Mutation Causes Paragangliomas (PGLs) in the French Canadians: New Insights on the SDHC-Related PGL. 27700540 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR Attention Deficit Hyperactivity Disorder in Pediatric Patients with Pheochromocytoma and Paraganglioma. 27171833 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR Magnetic resonance imaging spectrum of succinate dehydrogenase-related infantile leukoencephalopathy. 26642834 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 GeneticVariation group CLINVAR Novel SDHB and TMEM127 Mutations in Patients with Pheochromocytoma/Paraganglioma Syndrome. 26960314 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery. 26719882 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR Rapid-sequence MRI for long-term surveillance for paraganglioma and phaeochromocytoma in patients with succinate dehydrogenase mutations. 27634942 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR Mediastinal paragangliomas related to SDHx gene mutations. 27785149 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 GeneticVariation group CLINVAR Identification of eight novel SDHB, SDHC, SDHD germline variants in Danish pheochromocytoma/paraganglioma patients. 27279923 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR Sporadic paraganglioma caused by de novo SDHB mutations in a 6-year-old girl. 26283294 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR Carney triad can be (rarely) associated with germline succinate dehydrogenase defects. 26173966 2016
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 GeneticVariation group CLINVAR Association of urinary bladder paragangliomas with germline mutations in the SDHB and VHL genes. 25683602 2015
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR Toward an improved definition of the genetic and tumor spectrum associated with SDH germ-line mutations. 25394176 2015
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245 2015
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.110 CausalMutation group CLINVAR 15 YEARS OF PARAGANGLIOMA: Clinical manifestations of paraganglioma syndromes types 1-5. 26273102 2015