| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | All-trans-retinoic acid (ATRA) treatment of MYCN/NCYM-amplified neuroblastoma CHP134 cells induced TAp63 and reduced p53 expressions, accompanied by downregulation of MYCN/NCYM expressions. | 31427086 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | We sought to determine a functional role for MYCNOS-01 in alveolar rhabdomyosarcoma and neuroblastoma cells and identify any associated regulatory effects between MYCN and MYCNOS-01. | 29466962 | 2018 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | NCYM upregulated N-Myc mRNA expression, NCYM RNA formed a complex with NonO protein, and knocking down NCYM expression reduced neuroblastoma cell proliferation. | 27748806 | 2016 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Taken together, these results demonstrate that CTCF cooperates with noncoding RNA MYCNOS to exhibit oncogenic activity that affects the aggressiveness and progression of NB through transcriptional upregulation of MYCN. | 26549029 | 2016 | ||||
|
0.080 | Biomarker | disease | BEFREE | These results reveal a novel function of NCYM as a regulator of Myc-nick production in human neuroblastomas. | 25896758 | 2015 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | In 36 MYCN-amplified primary human neuroblastomas, OCT4 mRNA expression was associated with unfavorable prognosis and was correlated with that of NCYM. | 25880909 | 2015 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | In primary human neuroblastomas, NCYM is 100% co-amplified and co-expressed with MYCN, and NCYM mRNA expression is associated with poor clinical outcome. | 24391509 | 2014 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Both DeltaMYCN and MYCNOS are expressed in all NBs examined. | 19615087 | 2009 |