| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | In the general population, 4 comparisons were carried out (C allele vs G allele, CC vs GG, GC + CC vs GG, and CC vs GC + GG) and found that <i>ADAM12 rs3740199</i> polymorphism was not associated with increased OA vulnerability. | 28721062 | 2017 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The association between ADAM 12 polymorphisms and knee OA risk was calculated by odds ratios (ORs) and 95% confidence intervals (CIs). | 28748424 | 2017 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The rs3740199 in ADAM12 was associated with knee OA susceptibility in Thai male patients, and individuals with the CC genotype carried the highest risk when compared with the GG and GC genotypes. | 26875044 | 2016 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | In summary, we have identified that the rs1871054 variant within the ADAM12 gene is a risk factor for increased osteoarthritis susceptibility and severity. | 25667922 | 2015 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | In conclusion, our data demonstrated the ADAM12 rs1871054 variant was found to be significantly associated with increased OA susceptibility in a Chinese Han population. | 25197389 | 2014 | ||||
|
0.080 | Biomarker | disease | BEFREE | Variants within ADAMTS5 and ADAM12 have been associated with osteoarthritis. | 23491141 | 2013 | ||||
|
0.080 | Biomarker | disease | BEFREE | ADAM12/meltrin alpha is a type I transmembrane multidomain protein involved in tumor progression and other severe diseases, including osteoarthritis, and as such could be considered as a potential drug target. | 19601832 | 2009 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | We investigated the potential role of two single nucleotide polymorphisms (SNP) of the ADAM12 gene in susceptibility to radiographic knee OA and its progression in an Estonian cohort. | 19268722 | 2009 |