Source: GWASCAT ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1301
Gene Symbol: COL11A1
COL11A1 		0.440 GeneticVariation disease GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.440 GeneticVariation disease GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
Entrez Id: 1301
Gene Symbol: COL11A1
COL11A1 		0.440 GeneticVariation disease GWASCAT A common missense variant in the COL11A1 gene also associates with hip osteoarthritis (rs3753841, frequency 61%, P = 5.2 × 10<sup>-10</sup>, OR = 1.08, p.Pro1284Leu). 30374069 2018
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.440 GeneticVariation disease GWASCAT Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018
Entrez Id: 3077
Gene Symbol: HFE
HFE 		0.420 GeneticVariation disease GWASCAT Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018
Entrez Id: 3589
Gene Symbol: IL11
IL11 		0.410 GeneticVariation disease GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
Entrez Id: 3589
Gene Symbol: IL11
IL11 		0.410 GeneticVariation disease GWASCAT Two associations are between rare or low-frequency missense variants and hip osteoarthritis, affecting the genes SMO (rs143083812, frequency 0.11%, odds ratio (OR) = 2.8, P = 7.9 × 10<sup>-12</sup>, p.Arg173Cys) and IL11 (rs4252548, frequency 2.08%, OR = 1.30, P = 2.1 × 10<sup>-11</sup>, p.Arg112His). 30374069 2018
Entrez Id: 6608
Gene Symbol: SMO
SMO 		0.410 GeneticVariation disease GWASCAT Two associations are between rare or low-frequency missense variants and hip osteoarthritis, affecting the genes SMO (rs143083812, frequency 0.11%, odds ratio (OR) = 2.8, P = 7.9 × 10<sup>-12</sup>, p.Arg173Cys) and IL11 (rs4252548, frequency 2.08%, OR = 1.30, P = 2.1 × 10<sup>-11</sup>, p.Arg112His). 30374069 2018
Entrez Id: 150356
Gene Symbol: CHADL
CHADL 		0.410 GeneticVariation disease GWASCAT Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018
Entrez Id: 3697
Gene Symbol: ITIH1
ITIH1 		0.400 GeneticVariation disease GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
Entrez Id: 4054
Gene Symbol: LTBP3
LTBP3 		0.400 GeneticVariation disease GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
Entrez Id: 23245
Gene Symbol: ASTN2
ASTN2 		0.400 GeneticVariation disease GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
Entrez Id: 3371
Gene Symbol: TNC
TNC 		0.400 GeneticVariation disease GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.400 GeneticVariation disease GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2 		0.400 GeneticVariation disease GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
Entrez Id: 27145
Gene Symbol: FILIP1
FILIP1 		0.400 GeneticVariation disease GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
Entrez Id: 4010
Gene Symbol: LMX1B
LMX1B 		0.400 GeneticVariation disease GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
Entrez Id: 9734
Gene Symbol: HDAC9
HDAC9 		0.400 GeneticVariation disease GWASCAT Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis. 29559693 2018
Entrez Id: 9734
Gene Symbol: HDAC9
HDAC9 		0.400 GeneticVariation disease GWASCAT Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018
Entrez Id: 4010
Gene Symbol: LMX1B
LMX1B 		0.400 GeneticVariation disease GWASCAT Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2 		0.400 GeneticVariation disease GWASCAT Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018
Entrez Id: 3371
Gene Symbol: TNC
TNC 		0.400 GeneticVariation disease GWASCAT Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018
Entrez Id: 27145
Gene Symbol: FILIP1
FILIP1 		0.400 GeneticVariation disease GWASCAT Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018
Entrez Id: 3697
Gene Symbol: ITIH1
ITIH1 		0.400 GeneticVariation disease GWASCAT Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018
Entrez Id: 4054
Gene Symbol: LTBP3
LTBP3 		0.400 GeneticVariation disease GWASCAT Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018