Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group BEFREE The highly tissue-specific expression profile, androgen regulation, chromosomal localization, and expression profile of AIbZIP in prostate tumors suggest that AIbZIP may play an important role in prostate cancer and in androgen receptor signaling in prostate cells. 11830526 2002
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group BEFREE Therefore, we searched for targets of the AR that may contribute to these anabolic processes and could be amenable to therapeutic intervention by virtue of differential expression in prostate tumours. 21602788 2011
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group LHGDN Androgen receptor auto-regulates its expression by a negative feedback loop through upregulation of IFI16 protein. 16494870 2006
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.600 AlteredExpression group BEFREE Immunofluorescence data and western blot analyses determined that a lentivirus containing a 5'UTR derived from FGF-2 is the best candidate for directing selective gene expression in the prostate tumors of PTEN(-/-) mice in vivo. 21921943 2012
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group LHGDN Androgen receptor negatively influences the expression of chemokine receptors (CXCR4, CCR1) and ligand-mediated migration in prostate cancer DU-145. 16969502 2006
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group BEFREE Immunohistochemistry shows that LATS2 and AR are localized within the prostate epithelium and that LATS2 expression is lower in human prostate tumor samples than in normal prostate. 15131260 2004
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.600 AlteredExpression group BEFREE In this study, we show that patients who develop prostate tumors with low levels of PTEN and high levels of HER2/3 have a poor prognosis. 21930937 2011
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.600 AlteredExpression group LHGDN FAS expression inversely correlates with PTEN level in prostate cancer and a PI 3-kinase inhibitor synergizes with FAS siRNA to induce apoptosis. 15897909 2005
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group BEFREE Our findings reveal novel mechanisms of AR transcription, which is dynamically regulated in prostate tumor progression. 30027545 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.600 AlteredExpression group LHGDN Lower levels of nuclear beta-catenin predict for a poorer prognosis in localized prostate cancer. 15455387 2005
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.600 AlteredExpression group LHGDN Overexpression of E-cadherin and beta-catenin proteins in metastatic prostate cancer cells in bone. 18008331 2008
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group LHGDN Differently regulated androgen receptor transcriptional complex in prostate cancer compared with normal prostate. 15948728 2005
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group LHGDN A central domain of cyclin D1 mediates nuclear receptor corepressor activity. 15558026 2005
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group LHGDN Elevated E2F1 inhibits transcription of the androgen receptor in metastatic hormone-resistant prostate cancer. 17178887 2006
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group LHGDN Prolonged androgen receptor loading onto chromatin and the efficient recruitment of p160 coactivators contribute to androgen-independent growth of prostate cancer cells. 18780293 2008
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group LHGDN Membrane androgen receptor activation induces apoptotic regression of human prostate cancer cells in vitro and in vivo. 15585562 2005
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group BEFREE LSD1 in association with the androgen receptor (AR) controls androgen-dependent gene expression and prostate tumor cell proliferation, thus highlighting LSD1 as a drug target. 22447389 2012
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group BEFREE Analysis of human prostate tumors indicates that several tumors express higher levels of this truncated AR than noncancerous prostate tissue. 17909000 2007
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group LHGDN Pomegranate polyphenols down-regulate expression of androgen-synthesizing genes in human prostate cancer cells overexpressing the androgen receptor. 18479901 2008
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.600 AlteredExpression group BEFREE IGF-IR expression positively correlates with PTEN and inversely correlates with NRP2 in prostate tumors. 22777769 2012
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group LHGDN Cyclin-dependent kinase 6 associates with the androgen receptor and enhances its transcriptional activity in prostate cancer cells. 15790678 2005
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.600 AlteredExpression group BEFREE Here, we provide evidence that PTEN loss in prostate tumours upregulates the expression of ADAM17, thereby activating NOTCH signalling. 27941799 2016
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group BEFREE One common change in prostate tumors is overexpression of the AR, which has been shown to lead to androgen-independent growth of prostate cancer cells. 18469090 2008
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group LHGDN Phosphoinositide 3-OH kinase p85alpha and p110beta are essential for androgen receptor transactivation and tumor progression in prostate cancers. 18372911 2008
Entrez Id: 367
Gene Symbol: AR
AR 		0.600 AlteredExpression group LHGDN Androgen receptor as a licensing factor for DNA replication in androgen-sensitive prostate cancer cells. 17015840 2006