Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.300 Biomarker phenotype CTD_human Claudins, VEGF, Nrf2, Keap1, and Nonspecific Airway Hyper-Reactivity Are Increased in Mice Co-Exposed to Allergen and Acrolein. 30608172 2019
Entrez Id: 1364
Gene Symbol: CLDN4
CLDN4 		0.300 Biomarker phenotype CTD_human Claudins, VEGF, Nrf2, Keap1, and Nonspecific Airway Hyper-Reactivity Are Increased in Mice Co-Exposed to Allergen and Acrolein. 30608172 2019
Entrez Id: 7122
Gene Symbol: CLDN5
CLDN5 		0.300 Biomarker phenotype CTD_human Claudins, VEGF, Nrf2, Keap1, and Nonspecific Airway Hyper-Reactivity Are Increased in Mice Co-Exposed to Allergen and Acrolein. 30608172 2019
Entrez Id: 85480
Gene Symbol: TSLP
TSLP 		0.300 Therapeutic phenotype CTD_human Short Thymic Stromal Lymphopoietin Attenuates Toluene Diisocyanate-induced Airway Inflammation and Inhibits High Mobility Group Box 1-Receptor for Advanced Glycation End Products and Long Thymic Stromal Lymphopoietin Expression. 28329851 2017
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		0.300 Biomarker phenotype CTD_human Gene expressions changes in bronchial epithelial cells: markers for respiratory sensitizers and exploration of the NRF2 pathway. 24211530 2014
Entrez Id: 3309
Gene Symbol: HSPA5
HSPA5 		0.300 Biomarker phenotype CTD_human Gene expressions changes in bronchial epithelial cells: markers for respiratory sensitizers and exploration of the NRF2 pathway. 24211530 2014
Entrez Id: 7378
Gene Symbol: UPP1
UPP1 		0.300 Biomarker phenotype CTD_human Gene expressions changes in bronchial epithelial cells: markers for respiratory sensitizers and exploration of the NRF2 pathway. 24211530 2014
Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1 		0.300 Therapeutic phenotype CTD_human Respiratory syncytial virus reverses airway hyperresponsiveness to methacholine in ovalbumin-sensitized mice. 23056391 2012
Entrez Id: 1232
Gene Symbol: CCR3
CCR3 		0.300 Biomarker phenotype CTD_human Association of the CCR3 gene polymorphism with aspirin exacerbated respiratory disease. 20022477 2010
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker phenotype CTD_human Inflammation and functional outcome in diisocyanate-induced asthma after cessation of exposure. 18394133 2008
Entrez Id: 3565
Gene Symbol: IL4
IL4 		0.300 Biomarker phenotype CTD_human Inflammation and functional outcome in diisocyanate-induced asthma after cessation of exposure. 18394133 2008
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.300 Biomarker phenotype CTD_human Inflammation and functional outcome in diisocyanate-induced asthma after cessation of exposure. 18394133 2008
Entrez Id: 3600
Gene Symbol: IL15
IL15 		0.300 Biomarker phenotype CTD_human Inflammation and functional outcome in diisocyanate-induced asthma after cessation of exposure. 18394133 2008
Entrez Id: 5777
Gene Symbol: PTPN6
PTPN6 		0.300 Biomarker phenotype CTD_human Tyrosine phosphatase SHP-1 in oxidative stress and development of allergic airway inflammation. 18441283 2008
Entrez Id: 55630
Gene Symbol: SLC39A4
SLC39A4 		0.300 Biomarker phenotype CTD_human Anti-inflammatory effects of zinc and alterations in zinc transporter mRNA in mouse models of allergic inflammation. 17085522 2007
Entrez Id: 6355
Gene Symbol: CCL8
CCL8 		0.300 Biomarker phenotype CTD_human Anti-inflammatory effects of zinc and alterations in zinc transporter mRNA in mouse models of allergic inflammation. 17085522 2007
Entrez Id: 6356
Gene Symbol: CCL11
CCL11 		0.300 Biomarker phenotype CTD_human Anti-inflammatory effects of zinc and alterations in zinc transporter mRNA in mouse models of allergic inflammation. 17085522 2007
Entrez Id: 27173
Gene Symbol: SLC39A1
SLC39A1 		0.300 Biomarker phenotype CTD_human Anti-inflammatory effects of zinc and alterations in zinc transporter mRNA in mouse models of allergic inflammation. 17085522 2007
Entrez Id: 7782
Gene Symbol: SLC30A4
SLC30A4 		0.300 Biomarker phenotype CTD_human Anti-inflammatory effects of zinc and alterations in zinc transporter mRNA in mouse models of allergic inflammation. 17085522 2007
Entrez Id: 23516
Gene Symbol: SLC39A14
SLC39A14 		0.300 Biomarker phenotype CTD_human Anti-inflammatory effects of zinc and alterations in zinc transporter mRNA in mouse models of allergic inflammation. 17085522 2007
Entrez Id: 3269
Gene Symbol: HRH1
HRH1 		0.300 Biomarker phenotype CTD_human Histamine H1 receptors are involved in mouse nasal allergic responses: a demonstration with H1 receptor-deficient mice. 12095164 2002
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		0.300 Biomarker phenotype CTD_human TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. 10835634 2000
Entrez Id: 79054
Gene Symbol: TRPM8
TRPM8 		0.010 GeneticVariation phenotype LHGDN Collectively, our results suggest that this novel TRPM8 variant receptor may function as a modulator of respiratory physiology caused by cold air, and may partially explain asthmatic respiratory hypersensitivity to cold air. 18458237 2008