Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.020 GeneticVariation disease BEFREE TNFA haplotype AAACGGGGC (t-statistic = 3.32) and IL12B promoter haplotype TAG (t-statistic = 2.66) were associated with higher levels of (p < or = 0.01) rubella-IgG and IL-6 secretion, respectively. 20217072 2010
Entrez Id: 4580
Gene Symbol: MTX1
MTX1
0.010 Biomarker disease BEFREE MTX and tumor necrosis factor inhibitory therapy appeared to reduce immune responses to VV and HZ vaccine, but not to MMR and YF-revaccination. 28162821 2017
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
0.100 Biomarker disease BEFREE MMR administration before rubella testing was identified in 75.8% of perinatally-infected women (22/29) with a mean of 2 doses (range: 1-3 doses). 31451323 2019
Entrez Id: 3067
Gene Symbol: HDC
HDC
0.010 Biomarker disease BEFREE A 16-year-old male patient with acute lymphoblastic leukemia in complete remission and on maintenance treatment with weekly oral methotrexate and daily oral 6-mercaptopurine for 3 months was immunized in error with the WI-RA 27/3-HDC live attenuated rubella vaccine. 8636717 1995
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
0.010 Biomarker disease BEFREE A new MMR vaccine (JVC-001) was developed, using mumps RIT4385 strain in combination with Japanese measles AIK-C strain and rubella Takahashi strain (MR) vaccine. 30724658 2019
Entrez Id: 7051
Gene Symbol: TGM1
TGM1
0.010 GeneticVariation disease BEFREE Additional consanguinous pedigrees were also demonstrated to be unlinked both to TGM1 and to 2q33-35, suggesting the existence of at least a third disease-causing gene. 8845852 1996
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
0.010 GeneticVariation disease BEFREE All analytes required age partitioning except β-human chorionic gonadotropin (β-hCG), cancer antigen 15-3 (CA15-3), rubella immunoglobulin G (rubella IgG), and vitamin D. Several analytes including estradiol, progesterone, testosterone, follicle-stimulating hormone (FSH), luteinizing hormone (LH), free triiodothyronine (FT3), total triiodothyronine (TT3), total thyroxine (TT4), thyroid uptake, ferritin, intact parathyroid hormone (iPTH), total prostate-specific antigen (tPSA), free prostate-specific antigen (fPSA), cancer antigen 125 (CA125), creatine kinase MB (CK-MB), and myoglobin showed sex differences, observed mostly with the onset of puberty. 28723610 2018
Entrez Id: 4151
Gene Symbol: MB
MB
0.010 Biomarker disease BEFREE All analytes required age partitioning except β-human chorionic gonadotropin (β-hCG), cancer antigen 15-3 (CA15-3), rubella immunoglobulin G (rubella IgG), and vitamin D. Several analytes including estradiol, progesterone, testosterone, follicle-stimulating hormone (FSH), luteinizing hormone (LH), free triiodothyronine (FT3), total triiodothyronine (TT3), total thyroxine (TT4), thyroid uptake, ferritin, intact parathyroid hormone (iPTH), total prostate-specific antigen (tPSA), free prostate-specific antigen (fPSA), cancer antigen 125 (CA125), creatine kinase MB (CK-MB), and myoglobin showed sex differences, observed mostly with the onset of puberty. 28723610 2018
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
0.100 Biomarker disease BEFREE All subjects (n=758) received two doses of MMR (measles/mumps/rubella) vaccine. 22504412 2012
Entrez Id: 23586
Gene Symbol: DDX58
DDX58
0.010 GeneticVariation disease BEFREE An intronic SNP (rs669260) in the antiviral innate immune receptor gene, DDX58, was significantly associated with increased neutralizing antibody titers for both measles and rubella viral antigens post-MMR vaccination (p values 0.02 and 0.0002, respectively). 25139337 2014
Entrez Id: 7038
Gene Symbol: TG
TG
0.010 Biomarker disease BEFREE Antibodies against MMR and autoantibodies against thyroglobulin, thyroid peroxidase, pancreas islet cells (ICA), islet cell surface, glutamic acid decarboxylase 65k autoantibodies, and insulin were studied before, and 3 months after, vaccination with combined MMR vaccine in 386 school children between 11 and 13 years of age. 10390298 1999
Entrez Id: 7173
Gene Symbol: TPO
TPO
0.010 Biomarker disease BEFREE Antibodies against MMR and autoantibodies against thyroglobulin, thyroid peroxidase, pancreas islet cells (ICA), islet cell surface, glutamic acid decarboxylase 65k autoantibodies, and insulin were studied before, and 3 months after, vaccination with combined MMR vaccine in 386 school children between 11 and 13 years of age. 10390298 1999
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
0.100 Biomarker disease BEFREE Characterization of rubella-specific humoral immunity following two doses of MMR vaccine using proteome microarray technology. 29145521 2017
Entrez Id: 54842
Gene Symbol: MFSD6
MFSD6
0.040 Biomarker disease BEFREE Children vaccinated with the second dose of measles, mumps, rubella vaccine (MMR2) at 4-6 years of age were followed up to 12 years post-vaccination. 29317117 2018
Entrez Id: 27074
Gene Symbol: LAMP3
LAMP3
0.020 Biomarker disease BEFREE Consequently, RT-LAMP for rubella virus would be expected to be a reliable rapid diagnostic tool in the clinical setting. 16954259 2006
Entrez Id: 4045
Gene Symbol: LSAMP
LSAMP
0.020 Biomarker disease BEFREE Consequently, RT-LAMP for rubella virus would be expected to be a reliable rapid diagnostic tool in the clinical setting. 16954259 2006
Entrez Id: 10565
Gene Symbol: ARFGEF1
ARFGEF1
0.010 Biomarker disease BEFREE Determinants in the maturation of rubella virus p200 replicase polyprotein precursor. 22491463 2012
Entrez Id: 196528
Gene Symbol: ARID2
ARID2
0.010 Biomarker disease BEFREE Determinants in the maturation of rubella virus p200 replicase polyprotein precursor. 22491463 2012
Entrez Id: 1523
Gene Symbol: CUX1
CUX1
0.010 Biomarker disease BEFREE Determinants in the maturation of rubella virus p200 replicase polyprotein precursor. 22491463 2012
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
0.020 Biomarker disease BEFREE Ensuring full vaccination of school children and identifying strategies to reach adults with measles and rubella combined vaccines will be important to hasten elimination of rubella and prevent CRS outbreaks. 29550193 2018
Entrez Id: 4938
Gene Symbol: OAS1
OAS1
0.010 GeneticVariation disease BEFREE Furthermore, both global tests and individual haplotype analyses revealed significant associations between OAS1 haplotypes and rubella virus-specific cytokine secretion. 20079393 2010
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
0.100 Biomarker disease BEFREE Genetic polymorphisms associated with rubella virus-specific cellular immunity following MMR vaccination. 25098560 2014
Entrez Id: 406989
Gene Symbol: MIR206
MIR206
0.010 Biomarker disease BEFREE Human microRNAs (Hsa-mir-198 and Hsa-mir-206) are predicted to bind to influenza, rubella, or poliovirus genes. 18552348 2009
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.020 AlteredExpression disease BEFREE Immunoaffinity purification with these monoclonal antibodies made it evident that they are useful for obtaining large quantities of pure baculovirus-expressed rubella virus envelope protein E1. 7814545 1994
Entrez Id: 110006328
Gene Symbol: ERVK-32
ERVK-32
0.010 AlteredExpression disease BEFREE Immunoaffinity purification with these monoclonal antibodies made it evident that they are useful for obtaining large quantities of pure baculovirus-expressed rubella virus envelope protein E1. 7814545 1994