Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		0.300 Biomarker phenotype CTD_human Expression of inducible nitric oxide synthase in failing and non-failing human heart. 8745224 1996
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.010 AlteredExpression phenotype LHGDN Endotoxin-adapted septic shock leukocytes selectively alter production of sIL-1RA and IL-1beta. 11770040 2001
Entrez Id: 1440
Gene Symbol: CSF3
CSF3 		0.010 Biomarker phenotype LHGDN Peaks of endogenous G-CSF serum concentrations are followed by an increase in respiratory burst activity of granulocytes in patients with septic shock. 12027409 2002
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.030 Biomarker phenotype LHGDN Interleukin-10 controls the onset of irreversible septic shock. 12117955 2002
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A 		0.010 AlteredExpression phenotype LHGDN Elevated serum levels of the type I and type II receptors for tumor necrosis factor-alpha as predictive factors for ARF in patients with septic shock. 12500222 2003
Entrez Id: 7133
Gene Symbol: TNFRSF1B
TNFRSF1B 		0.010 AlteredExpression phenotype LHGDN Elevated serum levels of the type I and type II receptors for tumor necrosis factor-alpha as predictive factors for ARF in patients with septic shock. 12500222 2003
Entrez Id: 2152
Gene Symbol: F3
F3 		0.010 Biomarker phenotype LHGDN M type 1 and 3 group A streptococci stimulate tissue factor-mediated procoagulant activity in human monocytes and endothelial cells. 12654807 2003
Entrez Id: 2215
Gene Symbol: FCGR3B
FCGR3B 		0.010 Biomarker phenotype LHGDN FcgammaRIIIb and complement component C7 codeficiency in a patient with recurrence of fulminant meningococcal septic shock. 15889368 2005
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.030 Biomarker phenotype LHGDN Association of polymorphisms of IL and CD14 genes with acute severe pancreatitis and septic shock. 16038043 2005
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.310 AlteredExpression phenotype LHGDN Implication of Toll-like receptor and tumor necrosis factor alpha signaling in septic shock. 16135957 2005
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		0.010 AlteredExpression phenotype LHGDN Implication of Toll-like receptor and tumor necrosis factor alpha signaling in septic shock. 16135957 2005
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1 		0.010 Biomarker phenotype LHGDN Glucocorticoid receptor beta in acute and chronic inflammatory conditions: clinical implications. 16446173 2006
Entrez Id: 23564
Gene Symbol: DDAH2
DDAH2 		0.010 GeneticVariation phenotype LHGDN Septic shock is correlated with asymmetrical dimethyl arginine levels, which may be influenced by a polymorphism in the dimethylarginine dimethylaminohydrolase II gene: a prospective observational study. 17002794 2006
Entrez Id: 3329
Gene Symbol: HSPD1
HSPD1 		0.010 AlteredExpression phenotype LHGDN Extracellular heat shock protein 60 (Hsp60) levels in children with septic shock. 17588138 2007
Entrez Id: 923
Gene Symbol: CD6
CD6 		0.010 Biomarker phenotype LHGDN CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock. 17601777 2007
Entrez Id: 7450
Gene Symbol: VWF
VWF 		0.010 AlteredExpression phenotype LHGDN ADAMTS-13, von Willebrand factor and related parameters in severe sepsis and septic shock. 17764538 2007
Entrez Id: 11093
Gene Symbol: ADAMTS13
ADAMTS13 		0.010 AlteredExpression phenotype LHGDN ADAMTS-13, von Willebrand factor and related parameters in severe sepsis and septic shock. 17764538 2007
Entrez Id: 2638
Gene Symbol: GC
GC 		0.300 Biomarker phenotype CTD_human Comparison of rocket and crossed immuno-electrophoresis assays for determination of the level of actin complexing of Gc globulin. 17852808 2007
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.010 GeneticVariation phenotype LHGDN Interleukin-6 gene variants and the risk of sepsis development in children. 17869650 2007
Entrez Id: 834
Gene Symbol: CASP1
CASP1 		0.020 Biomarker phenotype LHGDN The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock. 17959595 2007
Entrez Id: 133
Gene Symbol: ADM
ADM 		0.020 Biomarker phenotype LHGDN Adrenomedullin and endothelial barrier function. 18000597 2007
Entrez Id: 1361
Gene Symbol: CPB2
CPB2 		0.010 Biomarker phenotype LHGDN Thrombin-activatable fibrinolysis inhibitor is associated with severity and outcome of severe meningococcal infection in children. 18021301 2008
Entrez Id: 728
Gene Symbol: C5AR1
C5AR1 		0.300 Biomarker phenotype CTD_human Disruption of the C5a receptor gene increases resistance to acute Gram-negative bacteremia and endotoxic shock: opposing roles of C3a and C5a. 18063050 2008
Entrez Id: 133
Gene Symbol: ADM
ADM 		0.020 AlteredExpression phenotype LHGDN Circulating precursor levels of endothelin-1 and adrenomedullin, two endothelium-derived, counteracting substances, in sepsis. 18080871 2008
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.010 AlteredExpression phenotype LHGDN Circulating precursor levels of endothelin-1 and adrenomedullin, two endothelium-derived, counteracting substances, in sepsis. 18080871 2008