Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.310 Biomarker phenotype CTD_human Akt Cys-310-targeted inhibition by hydroxylated benzene derivatives is tightly linked to their immunosuppressive effects. 20054000 2010
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.310 AlteredExpression phenotype LHGDN Implication of Toll-like receptor and tumor necrosis factor alpha signaling in septic shock. 16135957 2005
Entrez Id: 3122
Gene Symbol: HLA-DRA
HLA-DRA 		0.300 Biomarker phenotype CTD_human Human leucocyte antigen (HLA-DR) gene expression is reduced in sepsis and correlates with impaired TNFα response: A diagnostic tool for immunosuppression? 28771573 2017
Entrez Id: 358
Gene Symbol: AQP1
AQP1 		0.300 Biomarker phenotype CTD_human Induced expression and functional effects of aquaporin-1 in human leukocytes in sepsis. 24028651 2013
Entrez Id: 728
Gene Symbol: C5AR1
C5AR1 		0.300 Biomarker phenotype CTD_human Disruption of the C5a receptor gene increases resistance to acute Gram-negative bacteremia and endotoxic shock: opposing roles of C3a and C5a. 18063050 2008
Entrez Id: 2638
Gene Symbol: GC
GC 		0.300 Biomarker phenotype CTD_human Comparison of rocket and crossed immuno-electrophoresis assays for determination of the level of actin complexing of Gc globulin. 17852808 2007
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		0.300 Biomarker phenotype CTD_human Expression of inducible nitric oxide synthase in failing and non-failing human heart. 8745224 1996
Entrez Id: 2241
Gene Symbol: FER
FER 		0.100 GeneticVariation phenotype GWASCAT Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study. 25533491 2015
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.030 AlteredExpression phenotype LHGDN Selective excretion of anti-inflammatory cytokine interleukin-10 in a superantigen-inducing neonatal infectious disease. 19084429 2009
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.030 Biomarker phenotype LHGDN Association of polymorphisms of IL and CD14 genes with acute severe pancreatitis and septic shock. 16038043 2005
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.030 Biomarker phenotype LHGDN Interleukin-10 controls the onset of irreversible septic shock. 12117955 2002
Entrez Id: 133
Gene Symbol: ADM
ADM 		0.020 AlteredExpression phenotype LHGDN Circulating precursor levels of endothelin-1 and adrenomedullin, two endothelium-derived, counteracting substances, in sepsis. 18080871 2008
Entrez Id: 834
Gene Symbol: CASP1
CASP1 		0.020 AlteredExpression phenotype LHGDN Inflammasome mRNA expression in human monocytes during early septic shock. 18263805 2008
Entrez Id: 133
Gene Symbol: ADM
ADM 		0.020 Biomarker phenotype LHGDN Adrenomedullin and endothelial barrier function. 18000597 2007
Entrez Id: 834
Gene Symbol: CASP1
CASP1 		0.020 Biomarker phenotype LHGDN The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock. 17959595 2007
Entrez Id: 6523
Gene Symbol: SLC5A1
SLC5A1 		0.010 AlteredExpression phenotype LHGDN Sodium-dependent glucose transporter-1 as a novel immunological player in the intestinal mucosa. 18713983 2008
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.010 AlteredExpression phenotype LHGDN Vascular endothelial growth factor and soluble fms-like tyrosine kinase-1 in septic shock patients treated with direct hemoperfusion with a polymyxin B-immobilized fiber column. 18789115 2008
Entrez Id: 1401
Gene Symbol: CRP
CRP 		0.010 Biomarker phenotype LHGDN Our purpose was to investigate serum amyloid A (SAA) protein and C-reactive protein (CRP) as inflammatory markers of septic shock patients. 18385816 2008
Entrez Id: 91662
Gene Symbol: NLRP12
NLRP12 		0.010 AlteredExpression phenotype LHGDN Inflammasome mRNA expression in human monocytes during early septic shock. 18263805 2008
Entrez Id: 1361
Gene Symbol: CPB2
CPB2 		0.010 Biomarker phenotype LHGDN Thrombin-activatable fibrinolysis inhibitor is associated with severity and outcome of severe meningococcal infection in children. 18021301 2008
Entrez Id: 22861
Gene Symbol: NLRP1
NLRP1 		0.010 AlteredExpression phenotype LHGDN Inflammasome mRNA expression in human monocytes during early septic shock. 18263805 2008
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.010 AlteredExpression phenotype LHGDN Circulating precursor levels of endothelin-1 and adrenomedullin, two endothelium-derived, counteracting substances, in sepsis. 18080871 2008
Entrez Id: 29108
Gene Symbol: PYCARD
PYCARD 		0.010 AlteredExpression phenotype LHGDN Inflammasome mRNA expression in human monocytes during early septic shock. 18263805 2008
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.010 GeneticVariation phenotype LHGDN Staphylococcal toxic shock syndrome toxin-1 induces the translocation and secretion of high mobility group-1 protein from both activated T cells and monocytes. 19009026 2008
Entrez Id: 6289
Gene Symbol: SAA2
SAA2 		0.010 Biomarker phenotype LHGDN Our purpose was to investigate serum amyloid A (SAA) protein and C-reactive protein (CRP) as inflammatory markers of septic shock patients. 18385816 2008