Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.500 Biomarker disease CTD_human Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats. 23792339 2013
Entrez Id: 4825
Gene Symbol: NKX6-1
NKX6-1 		0.300 Biomarker disease CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366 2005
Entrez Id: 857
Gene Symbol: CAV1
CAV1 		0.300 Biomarker disease CTD_human Resveratrol enhances GLUT-4 translocation to the caveolar lipid raft fractions through AMPK/Akt/eNOS signalling pathway in diabetic myocardium. 18266981 2008
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.300 Biomarker disease CTD_human Investigation of ocular neovascularization-related genes and oxidative stress in diabetic rat eye tissues after resveratrol treatment. 22191573 2012
Entrez Id: 6517
Gene Symbol: SLC2A4
SLC2A4 		0.300 Biomarker disease CTD_human Taurine exerts hypoglycemic effect in alloxan-induced diabetic rats, improves insulin-mediated glucose transport signaling pathway in heart and ameliorates cardiac oxidative stress and apoptosis. 22138235 2012
Entrez Id: 1374
Gene Symbol: CPT1A
CPT1A 		0.300 Biomarker disease CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366 2005
Entrez Id: 641371
Gene Symbol: ACOT1
ACOT1 		0.300 Biomarker disease CTD_human Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone. 14563825 2004
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.300 Biomarker disease CTD_human Antioxidant activity of costunolide and eremanthin isolated from Costus speciosus (Koen ex. Retz) Sm. 20709041 2010
Entrez Id: 5105
Gene Symbol: PCK1
PCK1 		0.300 Biomarker disease CTD_human Insulinotropic effect of cinnamaldehyde on transcriptional regulation of pyruvate kinase, phosphoenolpyruvate carboxykinase, and GLUT4 translocation in experimental diabetic rats. 20363216 2010
Entrez Id: 3290
Gene Symbol: HSD11B1
HSD11B1 		0.300 Biomarker disease CTD_human Increased expression and activity of 11beta-HSD-1 in diabetic islets and prevention with troglitazone. 14697232 2004
Entrez Id: 6364
Gene Symbol: CCL20
CCL20 		0.300 Therapeutic disease CTD_human Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes. 21340626 2011
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.300 Biomarker disease CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366 2005
Entrez Id: 2820
Gene Symbol: GPD2
GPD2 		0.300 Biomarker disease CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366 2005
Entrez Id: 489
Gene Symbol: ATP2A3
ATP2A3 		0.300 Biomarker disease CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366 2005
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.300 Therapeutic disease CTD_human MnSOD and catalase transgenes demonstrate that protection of islets from oxidative stress does not alter cytokine toxicity. 15855331 2005
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.300 Therapeutic disease CTD_human Effect of age receptor blocker and/or anti-inflammatory coadministration in relation to glycation, oxidative stress and cytokine production in stz diabetic rats. 12123627 2002
Entrez Id: 3098
Gene Symbol: HK1
HK1 		0.300 Biomarker disease CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366 2005
Entrez Id: 5972
Gene Symbol: REN
REN 		0.300 Biomarker disease CTD_human Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis. 18829990 2008
Entrez Id: 155
Gene Symbol: ADRB3
ADRB3 		0.300 Biomarker disease CTD_human Role of beta-3-adrenoceptor in catecholamine-induced relaxations in gastric fundus from control and diabetic rats. 17622774 2007
Entrez Id: 5213
Gene Symbol: PFKM
PFKM 		0.300 Biomarker disease CTD_human Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone. 14563825 2004
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2 		0.300 Biomarker disease CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366 2005
Entrez Id: 5166
Gene Symbol: PDK4
PDK4 		0.300 Biomarker disease CTD_human Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone. 14563825 2004
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.300 Biomarker disease CTD_human Altered MAPK signaling in progressive deterioration of endothelial function in diabetic mice. 22933112 2012
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.300 Therapeutic disease CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366 2005
Entrez Id: 6514
Gene Symbol: SLC2A2
SLC2A2 		0.300 Biomarker disease CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366 2005