Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3643
Gene Symbol: INSR
INSR 		0.300 Biomarker disease CTD_human Effects of angiotensin II on insulin receptor binding and mRNA levels in normal and diabetic rats. 9243097 1997
Entrez Id: 57678
Gene Symbol: GPAM
GPAM 		0.300 Biomarker disease CTD_human Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats. 9452481 1998
Entrez Id: 2180
Gene Symbol: ACSL1
ACSL1 		0.300 Biomarker disease CTD_human Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats. 9452481 1998
Entrez Id: 6720
Gene Symbol: SREBF1
SREBF1 		0.300 Biomarker disease CTD_human Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets. 10900012 2000
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.300 Biomarker disease CTD_human Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site. 11696579 2001
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.300 Therapeutic disease CTD_human Effect of age receptor blocker and/or anti-inflammatory coadministration in relation to glycation, oxidative stress and cytokine production in stz diabetic rats. 12123627 2002
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A 		0.300 Therapeutic disease CTD_human Polyethylene glycolated recombinant TNF receptor I improves insulitis and reduces incidence of spontaneous and cyclophosphamide-accelerated diabetes in nonobese diabetic mice. 12193562 2002
Entrez Id: 6517
Gene Symbol: SLC2A4
SLC2A4 		0.300 Biomarker disease CTD_human Troglitazone improves GLUT4 expression in adipose tissue in an animal model of obese type 2 diabetes mellitus. 11947963 2002
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.300 Biomarker disease CTD_human Effect of age receptor blocker and/or anti-inflammatory coadministration in relation to glycation, oxidative stress and cytokine production in stz diabetic rats. 12123627 2002
Entrez Id: 1535
Gene Symbol: CYBA
CYBA 		0.300 Biomarker disease CTD_human Vascular NADH oxidase is involved in impaired endothelium-dependent vasodilation in OLETF rats, a model of type 2 diabetes. 11812764 2002
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE 		0.300 Biomarker disease CTD_human Myocardial effects of ethanol consumption in the rat with streptozotocin-induced diabetes. 12198386 2002
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Polyethylene glycolated recombinant TNF receptor I improves insulitis and reduces incidence of spontaneous and cyclophosphamide-accelerated diabetes in nonobese diabetic mice. 12193562 2002
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD 		0.300 Biomarker disease CTD_human Myocardial effects of ethanol consumption in the rat with streptozotocin-induced diabetes. 12198386 2002
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker disease CTD_human Effect of age receptor blocker and/or anti-inflammatory coadministration in relation to glycation, oxidative stress and cytokine production in stz diabetic rats. 12123627 2002
Entrez Id: 5578
Gene Symbol: PRKCA
PRKCA 		0.300 Biomarker disease CTD_human Myocardial effects of ethanol consumption in the rat with streptozotocin-induced diabetes. 12198386 2002
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.300 Biomarker disease CTD_human Effect of age receptor blocker and/or anti-inflammatory coadministration in relation to glycation, oxidative stress and cytokine production in stz diabetic rats. 12123627 2002
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		0.300 Biomarker disease CTD_human Relationship between peroxisome proliferator-activated receptors (PPAR alpha and PPAR gamma) and endothelium-dependent relaxation in streptozotocin-induced diabetic rats. 12967931 2003
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.300 Biomarker disease CTD_human Relationship between peroxisome proliferator-activated receptors (PPAR alpha and PPAR gamma) and endothelium-dependent relaxation in streptozotocin-induced diabetic rats. 12967931 2003
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.300 Biomarker disease CTD_human Endothelin-1-mediated alteration of metallothionein and trace metals in the liver and kidneys of chronically diabetic rats. 12458661 2003
Entrez Id: 5465
Gene Symbol: PPARA
PPARA 		0.300 Biomarker disease CTD_human Relationship between peroxisome proliferator-activated receptors (PPAR alpha and PPAR gamma) and endothelium-dependent relaxation in streptozotocin-induced diabetic rats. 12967931 2003
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.300 Biomarker disease CTD_human Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy. 14514642 2003
Entrez Id: 1535
Gene Symbol: CYBA
CYBA 		0.300 Biomarker disease CTD_human Relationship between peroxisome proliferator-activated receptors (PPAR alpha and PPAR gamma) and endothelium-dependent relaxation in streptozotocin-induced diabetic rats. 12967931 2003
Entrez Id: 641371
Gene Symbol: ACOT1
ACOT1 		0.300 Biomarker disease CTD_human Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone. 14563825 2004
Entrez Id: 3290
Gene Symbol: HSD11B1
HSD11B1 		0.300 Biomarker disease CTD_human Increased expression and activity of 11beta-HSD-1 in diabetic islets and prevention with troglitazone. 14697232 2004
Entrez Id: 5213
Gene Symbol: PFKM
PFKM 		0.300 Biomarker disease CTD_human Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone. 14563825 2004