| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.400 | GeneticVariation | disease | BEFREE | Association study of 5-HT1A, 5-HT2A polymorphisms with schizophrenia and major depressive disorder in the Han Chinese population. | 27756686 | 2016 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | Six polymorphisms in four genes related to the serotonin system, including the HTTLPR and HTTVNTR in the SLC6A4 gene, rs6295 in the HTR1A gene, rs11568817 and rs130058 in the HTR1B gene, and rs6313 in the HTR2A gene, were studied in 420 patients with MD to investigate the relationship between these genes and suicidal ideation in MD. | 19897250 | 2009 | ||||
|
0.400 | Biomarker | disease | PSYGENET | 5-HT2A receptor -1438 G/A polymorphism and serotonergic antidepressant-induced sexual dysfunction in male patients with major depressive disorder: a prospective exploratory study. | 22612784 | 2012 | ||||
|
0.400 | Biomarker | disease | BEFREE | HTR2A is associated with SSRI response in major depressive disorder in a Japanese cohort. | 19937159 | 2010 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | Our results suggest that the 102T/C polymorphism in 5-HT2A receptor gene is primarily associated with suicidal ideation in patients with major depression.Am.J. Med.Genet.(Neuropsychiatr.Genet.)96:56-60, 2000. | 10686553 | 2000 | ||||
|
0.400 | Biomarker | disease | PSYGENET | Influence of 5-HTR2A genetic polymorphisms on the efficacy of antidepressants in the treatment of major depressive disorder: a meta-analysis. | 25108775 | 2014 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | The 102T/C polymorphism of the 5-HT(2A) receptor gene was analyzed in 159 patients with major depression (DSM-IV criteria) and 164 unrelated and healthy controls using a case control design. | 11803534 | 2001 | ||||
|
0.400 | AlteredExpression | disease | BEFREE | While further work is needed to identify the actual functional genetic variants involved, these results suggest that a relationship exists between genetic variation in HTR2A and either 5-HTT expression or central serotonergic transmission that influences the therapeutic response to 5-HTT inhibition in major depression. | 20047709 | 2010 |