| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.400 | GeneticVariation | disease | BEFREE | Our results suggest that the 102T/C polymorphism in 5-HT2A receptor gene is primarily associated with suicidal ideation in patients with major depression.Am.J. Med.Genet.(Neuropsychiatr.Genet.)96:56-60, 2000. | 10686553 | 2000 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | The 102T/C polymorphism of the 5-HT(2A) receptor gene was analyzed in 159 patients with major depression (DSM-IV criteria) and 164 unrelated and healthy controls using a case control design. | 11803534 | 2001 | ||||
|
0.400 | AlteredExpression | disease | BEFREE | While further work is needed to identify the actual functional genetic variants involved, these results suggest that a relationship exists between genetic variation in HTR2A and either 5-HTT expression or central serotonergic transmission that influences the therapeutic response to 5-HTT inhibition in major depression. | 20047709 | 2010 | ||||
|
0.400 | Biomarker | disease | PSYGENET | Converging translational evidence for the involvement of the serotonin 2A receptor gene in major depressive disorder. | 24801750 | 2014 | ||||
|
0.400 | Biomarker | disease | PSYGENET | Association of the T102C polymorphism in the HTR2A gene with major depressive disorder, bipolar disorder, and schizophrenia. | 24962835 | 2014 | ||||
|
0.400 | Biomarker | disease | PSYGENET | Association of HTR2A T102C and A-1438G polymorphisms with susceptibility to major depressive disorder: a meta-analysis. | 25270656 | 2014 | ||||
|
0.400 | Biomarker | disease | PSYGENET | 5-HT2A receptor -1438 G/A polymorphism and serotonergic antidepressant-induced sexual dysfunction in male patients with major depressive disorder: a prospective exploratory study. | 22612784 | 2012 | ||||
|
0.400 | Biomarker | disease | PSYGENET | Influence of 5-HTR2A genetic polymorphisms on the efficacy of antidepressants in the treatment of major depressive disorder: a meta-analysis. | 25108775 | 2014 |