| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.200 | Biomarker | disease | RGD | Experimental alcohol-related peripheral neuropathy: role of insulin/IGF resistance. | 23016131 | 2012 | ||||
|
0.200 | Biomarker | disease | RGD | Experimental alcohol-related peripheral neuropathy: role of insulin/IGF resistance. | 23016131 | 2012 | ||||
|
0.200 | Biomarker | disease | RGD | Experimental alcohol-related peripheral neuropathy: role of insulin/IGF resistance. | 23016131 | 2012 | ||||
|
0.020 | Biomarker | disease | BEFREE | Alcoholics with ALDH2*2 heterozygotes showed significantly lower sensory nerve action potential amplitudes of the sural and median nerves than those with ALDH2*1 homozygotes, suggesting that the accumulation of acetaldehyde due to ALDH2 inactivity is associated with alcoholic polyneuropathy. | 15182962 | 2004 | ||||
|
0.020 | Biomarker | disease | LHGDN | Association of aldehyde dehydrogenase-2 polymorphism with alcoholic polyneuropathy in humans. | 15182962 | 2004 | ||||
|
0.020 | GeneticVariation | disease | BEFREE | The results revealed that (1) the less active allele of the ADH2 gene (ADH2*1) is associated with an increased risk for alcohol dependence, alcohol-induced persistent amnestic disorder, alcohol withdrawal syndrome, and cancer of the upper GI tract; (2) the inactive allele of the ALDH2 gene (ALDH2*2) is associated with a decreased risk for alcohol dependence, and an increased risk for alcoholic polyneuropathy and cancer in the same region; and (3) these genetic variations modify clinical features of alcohol dependence. | 15542751 | 2004 | ||||
|
0.010 | GeneticVariation | disease | BEFREE | The results revealed that (1) the less active allele of the ADH2 gene (ADH2*1) is associated with an increased risk for alcohol dependence, alcohol-induced persistent amnestic disorder, alcohol withdrawal syndrome, and cancer of the upper GI tract; (2) the inactive allele of the ALDH2 gene (ALDH2*2) is associated with a decreased risk for alcohol dependence, and an increased risk for alcoholic polyneuropathy and cancer in the same region; and (3) these genetic variations modify clinical features of alcohol dependence. | 15542751 | 2004 |