Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3
0.510 Biomarker disease CTD_human ABCA3 mutations led to pulmonary fibrosis and emphysema with pulmonary hypertension in an 8-year-old girl. 26780485 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.510 Biomarker disease CTD_human Atomic layer deposition coating of carbon nanotubes with aluminum oxide alters pro-fibrogenic cytokine expression by human mononuclear phagocytes in vitro and reduces lung fibrosis in mice in vivo. 25216247 2015
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3
0.510 GeneticVariation disease BEFREE Usual interstitial pneumonia in an adolescent with ABCA3 mutations. 18628224 2008
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.510 Biomarker disease CTD_human Levels of cytokine in bronchoalveolar lavage (BAL) fluid in patients with pulmonary fibrosis due to sulfur mustard gas inhalation. 17266442 2007
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.510 GeneticVariation disease BEFREE Analysis of tumor necrosis factor-alpha, lymphotoxin-alpha, tumor necrosis factor receptor II, and interleukin-6 polymorphisms in patients with idiopathic pulmonary fibrosis. 11371414 2001
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.510 Biomarker disease RGD In conclusion, the lymphocytosis in BAL fluid of patients with NSIP and a subgroup of UIP is associated with the high levels of IL-6 and its sources are the epithelial cells of the small airway and the alveolar macrophages. 10988147 2000
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.510 Biomarker disease RGD To reveal a relation of IL-6 with the lymphocyte infiltration of NSIP, IL-6 was measured in BAL fluids of idiopathic NSIP (n = 7), idiopathic UIP (n = 16), and normal control subjects (n = 45). 10988147 2000
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.510 Biomarker disease RGD UIP cases were divided into two groups: high-UIP (n = 7) or low-UIP (n = 9) according to IL-6 levels greater than or within the 95 percentile of normal control subjects, respectively. 10988147 2000
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.510 Biomarker disease RGD IL-6 stained on epithelial cells of the bronchial tree and on alveolar macrophages of NSIP and UIP. 10988147 2000
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.510 Biomarker disease RGD Lymphocyte numbers and IL-6 levels in BAL fluids were higher in NSIP than those in UIP (p < 0.01, respectively), which were also higher when compared with those of normal control subjects (p < 0.01, respectively). 10988147 2000
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.510 Biomarker disease RGD IL-6-producing sites were assessed by IL-6 protein stain on biopsy specimens of NSIP, UIP, and normal lung of mediastinal tumors. 10988147 2000
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3
0.510 GeneticVariation disease ORPHANET
Entrez Id: 10144
Gene Symbol: FAM13A
FAM13A
0.500 Biomarker disease CTD_human Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. 28166215 2017
Entrez Id: 1832
Gene Symbol: DSP
DSP
0.500 Biomarker disease CTD_human Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. 28166215 2017
Entrez Id: 1832
Gene Symbol: DSP
DSP
0.500 SusceptibilityMutation disease ORPHANET
Entrez Id: 10144
Gene Symbol: FAM13A
FAM13A
0.500 SusceptibilityMutation disease ORPHANET
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B
0.400 AlteredExpression disease BEFREE Regulation of MUC5B Expression in Idiopathic Pulmonary Fibrosis. 28272906 2017
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B
0.400 Biomarker disease BEFREE TOLLIP, MUC5B, and the Response to N-Acetylcysteine among Individuals with Idiopathic Pulmonary Fibrosis. 26331942 2016
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B
0.400 GeneticVariation disease BEFREE MUC5B promoter polymorphism in Japanese patients with idiopathic pulmonary fibrosis. 25581455 2016
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B
0.400 GeneticVariation disease BEFREE A meta-analysis examining the association between the MUC5B rs35705950 T/G polymorphism and susceptibility to idiopathic pulmonary fibrosis. 25926289 2016
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B
0.400 GeneticVariation disease BEFREE The MUC5B promoter polymorphism is associated with idiopathic pulmonary fibrosis in a Mexican cohort but is rare among Asian ancestries. 25275363 2015
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B
0.400 GeneticVariation disease BEFREE The minor (T) allele of the MUC5B polymorphism was associated with concordant CT scan and histologic UIP diagnosis (P = .03). 25317858 2015
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B
0.400 GeneticVariation disease BEFREE The MUC5B variant is associated with idiopathic pulmonary fibrosis but not with systemic sclerosis interstitial lung disease in the European Caucasian population. 23940607 2014
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B
0.400 GeneticVariation disease BEFREE A common promoter polymorphism (rs35705950) in MUC5B, the gene encoding mucin 5B, is associated with idiopathic pulmonary fibrosis. 23692170 2013
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B
0.400 GeneticVariation disease BEFREE Mucin 5B promoter polymorphism is associated with idiopathic pulmonary fibrosis but not with development of lung fibrosis in systemic sclerosis or sarcoidosis. 23321605 2013