×
Entrez Id:
673
Gene Symbol:
BRAF
BRAF
0.050
GeneticVariation
group
BEFREE
Research has shown that a majority of melanomas and nevi exhibit an activating V600E (T1799A ) mutation in BRAF exon 15.
15811117
2005
×
Entrez Id:
673
Gene Symbol:
BRAF
BRAF
0.050
GeneticVariation
group
BEFREE
Somatic mutations of the BRAF gene are common in melanomas and nevi but the contribution of polymorphisms in this gene to melanoma or nevus susceptibility remains unclear.
16354196
2005
×
Entrez Id:
673
Gene Symbol:
BRAF
BRAF
0.050
GeneticVariation
group
BEFREE
Proto-oncogene B-Raf (BRAF ) mutation rates have been reported in nevi and melanomas of homogeneous Caucasian cohorts.
23906414
2014
×
Entrez Id:
673
Gene Symbol:
BRAF
BRAF
0.050
GeneticVariation
group
BEFREE
BRAF mutations in melanocytic tumors (nevi and melanomas ) from organ transplant recipients.
19919912
2010
×
Entrez Id:
673
Gene Symbol:
BRAF
BRAF
0.050
GeneticVariation
group
BEFREE
BRAF mutation status distinctly differs between BRAFi-MLs from melanomas and nevi biopsied in patients who do not receive BRAFi therapy.
26997441
2016
×
Entrez Id:
5894
Gene Symbol:
RAF1
RAF1
0.020
GeneticVariation
group
BEFREE
BRAF is a gene of the RAF family of kinases, frequently mutated in benign and malignant melanocytic tumors (nevi and melanomas ).
19919912
2010
×
Entrez Id:
3815
Gene Symbol:
KIT
KIT
0.010
GeneticVariation
group
BEFREE
No KIT gene mutations were detected in melanomas and nevi .
23742652
2013
×
Entrez Id:
22882
Gene Symbol:
ZHX2
ZHX2
0.010
GeneticVariation
group
BEFREE
BRAF is a gene of the RAF family of kinases, frequently mutated in benign and malignant melanocytic tumors (nevi and melanomas ).
19919912
2010
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.010
GeneticVariation
group
BEFREE
High frequency of PTEN mutations in nevi and melanomas from xeroderma pigmentosum patients.
24483290
2014
×
Entrez Id:
8314
Gene Symbol:
BAP1
BAP1
0.300
Biomarker
group
CTD_human
Germline mutations in BAP1 predispose to melanocytic tumors.
21874003
2011
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
0.020
Biomarker
group
BEFREE
We evaluated a fluorescence in situ hybridization (FISH) assay, which has previously been shown to be of value for the diagnosis of melanocytic nevi and melanomas of the skin, using probes targeting 6p25 (RREB1), 6q23 (MYB), 11q13 (CCND1 ) and centromere 6 (CEP6), for its potential to assist in the distinction of conjunctival melanocytic nevi from melanomas.
20100177
2010
×
Entrez Id:
10573
Gene Symbol:
MRPL28
MRPL28
0.010
Biomarker
group
BEFREE
We performed p15 and p16 IHC analyses on a random series of nevi and melanomas .
27855847
2016
×
Entrez Id:
115482684
Gene Symbol:
H3P9
H3P9
0.010
Biomarker
group
BEFREE
We performed p15 and p16 IHC analyses on a random series of nevi and melanomas .
27855847
2016
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
0.010
Biomarker
group
BEFREE
We performed p15 and p16 IHC analyses on a random series of nevi and melanomas .
27855847
2016
×
Entrez Id:
10923
Gene Symbol:
SUB1
SUB1
0.010
Biomarker
group
BEFREE
We performed p15 and p16 IHC analyses on a random series of nevi and melanomas .
27855847
2016
×
Entrez Id:
317
Gene Symbol:
APAF1
APAF1
0.010
Biomarker
group
BEFREE
The immunohistochemical analysis revealed a significant difference in APAF-1 staining between nevi and melanomas .
15009102
2004
×
Entrez Id:
358
Gene Symbol:
AQP1
AQP1
0.010
Biomarker
group
BEFREE
Tumoral melanocytes in atypical nevi and melanomas were negative for AQP1 .
31305898
2019
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
0.010
Biomarker
group
BEFREE
Novel deletion loci at 5q35 and 17q21 (BRCA1 ) in atypical nevi and melanomas were identified.
19461239
2009
×
Entrez Id:
6239
Gene Symbol:
RREB1
RREB1
0.010
Biomarker
group
BEFREE
We evaluated a fluorescence in situ hybridization (FISH) assay, which has previously been shown to be of value for the diagnosis of melanocytic nevi and melanomas of the skin, using probes targeting 6p25 (RREB1 ), 6q23 (MYB), 11q13 (CCND1) and centromere 6 (CEP6), for its potential to assist in the distinction of conjunctival melanocytic nevi from melanomas.
20100177
2010
×
Entrez Id:
406988
Gene Symbol:
MIR205
MIR205
0.010
Biomarker
group
BEFREE
We validated those results in an independent set of nevi and melanomas by quantitative RT-PCR. miR-205 demonstrated a statistically significant, progressive diminution in expression from nevi to primary melanomas to metastatic melanomas.
22525428
2012
×
Entrez Id:
115482713
Gene Symbol:
H3P10
H3P10
0.010
Biomarker
group
BEFREE
We performed p15 and p16 IHC analyses on a random series of nevi and melanomas .
27855847
2016
×
Entrez Id:
6502
Gene Symbol:
SKP2
SKP2
0.010
Biomarker
group
BEFREE
Analysis of 25 samples of normal human skin, nevi, and melanomas revealed a positive correlation between c-Myc and SKP2 accumulation.
23792459
2014
×
Entrez Id:
1030
Gene Symbol:
CDKN2B
CDKN2B
0.010
Biomarker
group
BEFREE
We performed p15 and p16 IHC analyses on a random series of nevi and melanomas .
27855847
2016
×
Entrez Id:
29107
Gene Symbol:
NXT1
NXT1
0.010
Biomarker
group
BEFREE
We performed p15 and p16 IHC analyses on a random series of nevi and melanomas .
27855847
2016
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
0.020
AlteredExpression
group
BEFREE
Immunohistochemistry was used to analyze the expression of eIF-2alpha, eIF-4E, and cyclin D1 in melanocytic nevi and melanomas and the expression of eIF-2alpha in colonic adenomas and carcinomas.
12942578
2003