| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | group | BEFREE | Finally, these findings support a larger scale screening for HERPUD1 R50H and HFE H63D variants in the sub-group of 1ATD patients developing significant chronic hepatic injuries (hepatomegaly, chronic cholestasis, elevated liver enzymes) and at risk developing liver cirrhosis. | 28617828 | 2017 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Hemochromatosis is a common cause of chronic liver disease and HFE genotyping allows decisive and non-invasive diagnosis. | 27170390 | 2017 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Frequency of primary iron overload and HFE gene mutations (C282Y, H63D and S65C) in chronic liver disease patients in north India. | 17589946 | 2007 | ||||
|
0.080 | GeneticVariation | group | BEFREE | We aimed to determine the relationships between iron overload and HFE gene mutation in chronic liver disease in Turkey. | 17410459 | 2007 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Mutations in the HFE gene may influence development or progression of chronic liver disease by increasing iron stores or modulating immune responses. | 17101320 | 2006 | ||||
|
0.080 | GeneticVariation | group | BEFREE | The HFE gene mutations were confirmed in 24 of 41 (59%) cases with symptoms of chronic liver disease and iron overload, significantly more frequently in HCV-negative patients (12/14 vs. 12/27; chi2=8.28; p=0.05). | 16273299 | 2005 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Absence of hemochromatosis associated Cys282Tyr HFE gene mutation and low frequency of hemochromatosis phenotype in nonalcoholic chronic liver disease patients in India. | 14675248 | 2004 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Interaction between HFE mutations and exogenous risk factors was analyzed by collecting information on alcohol consumption, hepatitis B and C virus infections, and iron status at the time of diagnosis of chronic liver disease. | 11500061 | 2001 |