Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3082
Gene Symbol: HGF
HGF
0.300 Therapeutic disease CTD_human Double-blind, placebo-controlled study of HGF gene therapy in diabetic neuropathy. 26000320 2015
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
0.300 Biomarker disease CTD_human Heat shock protein 70 is necessary to improve mitochondrial bioenergetics and reverse diabetic sensory neuropathy following KU-32 therapy. 24263156 2014
Entrez Id: 1129
Gene Symbol: CHRM2
CHRM2
0.300 Therapeutic disease CTD_human The M2-muscarinic receptor inhibits the development of streptozotocin-induced neuropathy in mouse urinary bladder. 20624991 2010
Entrez Id: 2915
Gene Symbol: GRM5
GRM5
0.300 Biomarker disease CTD_human Regulation of increased glutamatergic input to spinal dorsal horn neurons by mGluR5 in diabetic neuropathic pain. 19840219 2010
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.300 Biomarker disease CTD_human Minocycline with aspirin: a therapeutic approach in the treatment of diabetic neuropathy. 20213226 2010
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 Biomarker disease CTD_human Minocycline with aspirin: a therapeutic approach in the treatment of diabetic neuropathy. 20213226 2010
Entrez Id: 4311
Gene Symbol: MME
MME
0.300 Biomarker disease CTD_human The roles of streptozotocin neurotoxicity and neutral endopeptidase in murine experimental diabetic neuropathy. 20148083 2009
Entrez Id: 3643
Gene Symbol: INSR
INSR
0.300 Biomarker disease CTD_human Early changes in insulin receptor signaling and pain sensation in streptozotocin-induced diabetic neuropathy in rats. 18331706 2008
Entrez Id: 6446
Gene Symbol: SGK1
SGK1
0.300 Biomarker disease CTD_human Expression of serum and glucocorticoid-inducible kinase1 in diabetic rats and its modulation by fluvastatin. 16696316 2005
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.300 Biomarker disease CTD_human Expression of serum and glucocorticoid-inducible kinase1 in diabetic rats and its modulation by fluvastatin. 16696316 2005
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.300 Biomarker disease CTD_human Asp299Gly and Thr399Ile genotypes of the TLR4 gene are associated with a reduced prevalence of diabetic neuropathy in patients with type 2 diabetes. 14693986 2004
Entrez Id: 836
Gene Symbol: CASP3
CASP3
0.300 Biomarker disease CTD_human Oxidative injury and apoptosis of dorsal root ganglion neurons in chronic experimental diabetic neuropathy. 12502508 2003
Entrez Id: 4908
Gene Symbol: NTF3
NTF3
0.300 Therapeutic disease CTD_human Continuous delivery of neurotrophin 3 by gene therapy has a neuroprotective effect in experimental models of diabetic and acrylamide neuropathies. 11779407 2001
Entrez Id: 847
Gene Symbol: CAT
CAT
0.300 Biomarker disease CTD_human Gene expression of antioxidant enzymes in experimental diabetic neuropathy. 10780678 2000