Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
0.040 GeneticVariation disease BEFREE RNF43 mutation frequently occurs with GNAS mutation and mucin hypersecretion in intraductal papillary neoplasms of the bile duct. 27864998 2017
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
0.040 GeneticVariation disease BEFREE GNAS and KRAS mutations are common in intraductal papillary neoplasms of the bile duct. 24312577 2013
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
0.040 GeneticVariation disease BEFREE GNAS Is frequently mutated in a specific subgroup of intraductal papillary neoplasms of the bile duct. 24061513 2013
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
0.040 GeneticVariation disease BEFREE GNAS codon 201 mutations are uncommon in intraductal papillary neoplasms of the bile duct. 22954004 2012
Entrez Id: 5979
Gene Symbol: RET
RET
0.020 GeneticVariation disease BEFREE In this case, several factors influence the frequency and the type of RET/PTC, such as exposure to radiation, age and histological variant of the papillary tumor. 10882153 2000
Entrez Id: 5726
Gene Symbol: TAS2R38
TAS2R38
0.020 GeneticVariation disease BEFREE In this case, several factors influence the frequency and the type of RET/PTC, such as exposure to radiation, age and histological variant of the papillary tumor. 10882153 2000
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
0.020 GeneticVariation disease BEFREE In this case, several factors influence the frequency and the type of RET/PTC, such as exposure to radiation, age and histological variant of the papillary tumor. 10882153 2000
Entrez Id: 2158
Gene Symbol: F9
F9
0.020 GeneticVariation disease BEFREE In this case, several factors influence the frequency and the type of RET/PTC, such as exposure to radiation, age and histological variant of the papillary tumor. 10882153 2000
Entrez Id: 8030
Gene Symbol: CCDC6
CCDC6
0.020 GeneticVariation disease BEFREE In this case, several factors influence the frequency and the type of RET/PTC, such as exposure to radiation, age and histological variant of the papillary tumor. 10882153 2000
Entrez Id: 8030
Gene Symbol: CCDC6
CCDC6
0.020 Biomarker disease BEFREE Here we show the detection by in situ hybridisation, of activated ret transcripts in human thyroid papillary neoplasms that were positive for PTC activation by Southern blot analysis. 1457350 1992
Entrez Id: 5726
Gene Symbol: TAS2R38
TAS2R38
0.020 Biomarker disease BEFREE Here we show the detection by in situ hybridisation, of activated ret transcripts in human thyroid papillary neoplasms that were positive for PTC activation by Southern blot analysis. 1457350 1992
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
0.020 Biomarker disease BEFREE Here we show the detection by in situ hybridisation, of activated ret transcripts in human thyroid papillary neoplasms that were positive for PTC activation by Southern blot analysis. 1457350 1992
Entrez Id: 2158
Gene Symbol: F9
F9
0.020 Biomarker disease BEFREE Here we show the detection by in situ hybridisation, of activated ret transcripts in human thyroid papillary neoplasms that were positive for PTC activation by Southern blot analysis. 1457350 1992
Entrez Id: 5979
Gene Symbol: RET
RET
0.020 Biomarker disease BEFREE Here we show the detection by in situ hybridisation, of activated ret transcripts in human thyroid papillary neoplasms that were positive for PTC activation by Southern blot analysis. 1457350 1992
Entrez Id: 5567
Gene Symbol: PRKACB
PRKACB
0.010 Biomarker disease BEFREE Recurrent Rearrangements in PRKACA and PRKACB in Intraductal Oncocytic Papillary Neoplasms of the Pancreas and Bile Duct. 31678302 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.010 Biomarker disease BEFREE Recurrent Mutations in APC and CTNNB1 and Activated Wnt/β-catenin Signaling in Intraductal Papillary Neoplasms of the Bile Duct: A Whole Exome Sequencing Study. 30212390 2018
Entrez Id: 54894
Gene Symbol: RNF43
RNF43
0.010 GeneticVariation disease BEFREE RNF43 mutation frequently occurs with GNAS mutation and mucin hypersecretion in intraductal papillary neoplasms of the bile duct. 27864998 2017
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.010 GeneticVariation disease BEFREE GNAS and KRAS mutations are common in intraductal papillary neoplasms of the bile duct. 24312577 2013
Entrez Id: 196
Gene Symbol: AHR
AHR
0.010 Biomarker disease BEFREE A renal cell strain derived from a human papillary tumor also showed sensitivity to AF, as well as AhR pathway activation and drug-induced apoptosis. 22485252 2012
Entrez Id: 207
Gene Symbol: AKT1
AKT1
0.010 GeneticVariation disease BEFREE High prevalence of PIK3CA/AKT pathway mutations in papillary neoplasms of the breast. 19898424 2010
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
0.010 PosttranslationalModification disease BEFREE These results indicate that microsatellite instability is a relatively frequent event in papillary neoplasms of the biliary tree but is not associated with hMLH1 promoter hypermethylation. 12481012 2002
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.010 AlteredExpression disease BEFREE We have previously reported that MUC2 apomucin was highly expressed in noninvasive tumors of the pancreas (intraductal papillary tumor [IdPT]) and liver (bile duct cystadenocarcinoma [BdCC]), which show more favorable outcomes than invasive carcinomas. 9042800 1997
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.010 Biomarker disease BEFREE Presence of wild-type p53 was found only in cell lines derived from either a low-grade, papillary tumor (RT4) or fetal bladder (FHs 738Bl). 7787250 1994
Entrez Id: 55717
Gene Symbol: WDR11
WDR11
0.010 GeneticVariation disease BEFREE In the present work we have found in a relatively large series of thyroid cancer patients (n = 161) that both HLA class I (B35) and class II (DR11) antigens are susceptibility factors only in the papillary tumor group of patients, B35 association p value is found at the limit of significance (pc(120) = 0.05); the follicular group did not show any HLA association, suggesting that the etiopathogenesis of each type of cancer is different. 7940496 1994