Our results showed that these three polymorphisms in the XRCC1 coding region were not associated with increased risk of NMSC in the total studied population.
In the current study, we aim to assess the impact of XRCC1R399Q and XRCC3 T241M polymorphisms on the risk of NMSC associated with sunlight and arsenic exposure.
We investigated the XRCC1arg399gln polymorphism and its interaction with carcinogen exposure in a large, population-based case-control study of non-melanoma skin cancer.