Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8787
Gene Symbol: RGS9
RGS9 		0.300 Therapeutic phenotype CTD_human Adaptive gene regulation in the Striatum of RGS9-deficient mice. 24663062 2014
Entrez Id: 9456
Gene Symbol: HOMER1
HOMER1 		0.300 Biomarker phenotype CTD_human Association of common genetic variants of HOMER1 gene with levodopa adverse effects in Parkinson's disease patients. 24126708 2014
Entrez Id: 8787
Gene Symbol: RGS9
RGS9 		0.300 Biomarker phenotype CTD_human Adaptive gene regulation in the Striatum of RGS9-deficient mice. 24663062 2014
Entrez Id: 1814
Gene Symbol: DRD3
DRD3 		0.300 Biomarker phenotype CTD_human Differential genetic susceptibility in diphasic and peak-dose dyskinesias in Parkinson's disease. 20945430 2011
Entrez Id: 5173
Gene Symbol: PDYN
PDYN 		0.300 Biomarker phenotype CTD_human L-DOPA-induced dyskinesia is associated with regional increase of striatal dynorphin peptides as elucidated by imaging mass spectrometry. 21737418 2011
Entrez Id: 5923
Gene Symbol: RASGRF1
RASGRF1 		0.300 Therapeutic phenotype CTD_human Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia. 21115823 2010
Entrez Id: 1812
Gene Symbol: DRD1
DRD1 		0.300 Biomarker phenotype CTD_human Genetic inactivation of dopamine D1 but not D2 receptors inhibits L-DOPA-induced dyskinesia and histone activation. 19520364 2009
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.300 Biomarker phenotype CTD_human Intense exercise potentiates oxidative stress in striatum of reserpine-treated animals. 19109989 2009
Entrez Id: 8787
Gene Symbol: RGS9
RGS9 		0.300 Therapeutic phenotype CTD_human RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease. 18160641 2007
Entrez Id: 8787
Gene Symbol: RGS9
RGS9 		0.300 Biomarker phenotype CTD_human RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease. 18160641 2007
Entrez Id: 1812
Gene Symbol: DRD1
DRD1 		0.300 Biomarker phenotype CTD_human A review of the receptor-binding and pharmacokinetic properties of dopamine agonists. 16982285 2006
Entrez Id: 2354
Gene Symbol: FOSB
FOSB 		0.300 Biomarker phenotype CTD_human Effect of antisense FosB and CREB on the expression of prodynorphin gene in rats with levodopa-induced dyskinesias. 17219962 2006
Entrez Id: 2643
Gene Symbol: GCH1
GCH1 		0.300 Therapeutic phenotype CTD_human Reversal of dyskinesias in an animal model of Parkinson's disease by continuous L-DOPA delivery using rAAV vectors. 15659429 2005
Entrez Id: 7054
Gene Symbol: TH
TH 		0.300 Therapeutic phenotype CTD_human Reversal of dyskinesias in an animal model of Parkinson's disease by continuous L-DOPA delivery using rAAV vectors. 15659429 2005
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker phenotype CTD_human Rapid onset of dyskinesia induced by olanzapine. 14629710 2003
Entrez Id: 2668
Gene Symbol: GDNF
GDNF 		0.300 Therapeutic phenotype CTD_human GDNF reverses priming for dyskinesia in MPTP-treated, L-DOPA-primed common marmosets. 11168568 2001
Entrez Id: 1812
Gene Symbol: DRD1
DRD1 		0.300 Biomarker phenotype CTD_human Effects of oligonucleotide antisense to dopamine D(1A) receptor messenger RNA in a rodent model of levodopa-induced dyskinesia. 10858612 2000
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker phenotype CTD_human Dopamine D2 receptor gene polymorphism and the risk of levodopa-induced dyskinesias in PD. 10534246 1999
Entrez Id: 5173
Gene Symbol: PDYN
PDYN 		0.300 Biomarker phenotype CTD_human L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA. 9767399 1998
Entrez Id: 2571
Gene Symbol: GAD1
GAD1 		0.300 Biomarker phenotype CTD_human L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA. 9767399 1998
Entrez Id: 5179
Gene Symbol: PENK
PENK 		0.300 Biomarker phenotype CTD_human L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA. 9767399 1998
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker phenotype CTD_human Felbamate, an anti-convulsive drug, has anti-parkinsonian potential in rats. 7845605 1994
Entrez Id: 1812
Gene Symbol: DRD1
DRD1 		0.300 Biomarker phenotype CTD_human Felbamate, an anti-convulsive drug, has anti-parkinsonian potential in rats. 7845605 1994
Entrez Id: 885
Gene Symbol: CCK
CCK 		0.300 Therapeutic phenotype CTD_human CCK-8S inhibits L-dopa-induced dyskinesias in parkinsonian squirrel monkeys. 2320253 1990